TCCA/ ncs促进β, γ-不饱和化合物级联环化:异恶唑啉和吡唑啉的合成

Khidir Tajelseir Othman, Nibras Ahmed Elaas
{"title":"TCCA/ ncs促进β, γ-不饱和化合物级联环化:异恶唑啉和吡唑啉的合成","authors":"Khidir Tajelseir Othman, Nibras Ahmed Elaas","doi":"10.4236/ijoc.2021.114013","DOIUrl":null,"url":null,"abstract":"2-Isoxazolines and 2-pyrazolines have been derived from oxime and hydrazone derivatives reacted with N-chlorosuccinimide (NCS) and trichloroisocyanuric acid (TCCA). Cyclization strategy is developed for the reaction of β, γ-unsaturated hydrazones with the TCCA to drive 2-pyrazolines and the reaction of β, γ-unsaturated oximes with NCS to derive 2-isoxalzolines. Structures of all new 2-isoxazolines and 2-pyrazolines have been elucidated by microanalyses, 1H, 13C NMR and Mass spectroscopies.","PeriodicalId":64796,"journal":{"name":"有机化学国际期刊(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"TCCA/NCS-Promoted Cascade Cyclization of β, γ-Unsaturated Compounds: Synthesis of Isoxazolines and Pyrazolines\",\"authors\":\"Khidir Tajelseir Othman, Nibras Ahmed Elaas\",\"doi\":\"10.4236/ijoc.2021.114013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"2-Isoxazolines and 2-pyrazolines have been derived from oxime and hydrazone derivatives reacted with N-chlorosuccinimide (NCS) and trichloroisocyanuric acid (TCCA). Cyclization strategy is developed for the reaction of β, γ-unsaturated hydrazones with the TCCA to drive 2-pyrazolines and the reaction of β, γ-unsaturated oximes with NCS to derive 2-isoxalzolines. Structures of all new 2-isoxazolines and 2-pyrazolines have been elucidated by microanalyses, 1H, 13C NMR and Mass spectroscopies.\",\"PeriodicalId\":64796,\"journal\":{\"name\":\"有机化学国际期刊(英文)\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"有机化学国际期刊(英文)\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.4236/ijoc.2021.114013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"有机化学国际期刊(英文)","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.4236/ijoc.2021.114013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

2-异恶唑啉和2-吡唑啉是由肟和腙衍生物与n -氯丁二酰亚胺(NCS)和三氯异氰尿酸(TCCA)反应而得。建立了β, γ-不饱和腙与TCCA反应生成2-吡唑啉和β, γ-不饱和肟与NCS反应生成2-异草唑啉的环化策略。所有新的2-异恶唑啉类和2-吡唑啉类化合物的结构已通过微量分析、1H、13C NMR和质谱进行了鉴定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
TCCA/NCS-Promoted Cascade Cyclization of β, γ-Unsaturated Compounds: Synthesis of Isoxazolines and Pyrazolines
2-Isoxazolines and 2-pyrazolines have been derived from oxime and hydrazone derivatives reacted with N-chlorosuccinimide (NCS) and trichloroisocyanuric acid (TCCA). Cyclization strategy is developed for the reaction of β, γ-unsaturated hydrazones with the TCCA to drive 2-pyrazolines and the reaction of β, γ-unsaturated oximes with NCS to derive 2-isoxalzolines. Structures of all new 2-isoxazolines and 2-pyrazolines have been elucidated by microanalyses, 1H, 13C NMR and Mass spectroscopies.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
297
期刊最新文献
A Novel Synthesis Process of Cholesterol Ester by the Cross-Coupling of Cholesterol and Aroyl Chlorides. Synthesis and Antitumor Activity of 3-[2-(4-Hydroxy-Phenyl)-Ethyl]-Benzo[d] Isoxazole-4,6-Diol Copper-Catalyzed C-C(O)C Bond Cleavage of Monoalkylated β-Diketone: Synthesis of α,β-Unsaturated Ketones Chemotaxonomic Study of the Covid-Organics of Madagascar Based on the Chemical Composition of Their Essential Oils Hirshfeld Surface Analysis for Investigation of Intermolecular Interaction of Molecular Crystals
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1