鼻腔外结节型自然杀伤/T细胞淋巴瘤模拟骨软化症并伴有骨盆中的并发B淋巴瘤:病例报告。

IF 0.8 4区 医学 Q4 PATHOLOGY Indian Journal of Pathology and Microbiology Pub Date : 2024-01-01 DOI:10.4103/ijpm.ijpm_296_22
Frida S Colín-Guadarrama, Violeta E Flores-Solano, Argelia Berenice-Rodríguez, Víctor H Toral-Rizo
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引用次数: 0

摘要

鼻腔外结节自然杀伤细胞/T细胞淋巴瘤(EN-NK/T-CL-NT)是一种非霍奇金外结节淋巴瘤,因其侵袭性而预后不良。这种肿瘤主要侵犯鼻旁窦、鼻咽、口咽、口腔、上颚,很少侵犯肠、胃和皮肤区域。50 岁女性,曾患鼻腔和盆腔淋巴瘤。无肿瘤四年后,面部不对称,伴有睑下、鼻和唇水肿。口腔内检查发现大面积溃疡,提示骨坏死。牙龈活检显示鼻腔外结节性 NK/T 细胞淋巴瘤(EN-NK/T-CL-NT)。在这个病例中,我们突出了EN-NK/T-CL-NT的特征,表现为类似骨坏死。不幸的是,这种肿瘤的性质导致了患者的死亡。对癌症患者进行临床随访,对于弥补和/或减少治疗并发症,以及识别第二原发性肿瘤或潜在疾病的扩散至关重要。
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Extranodal natural killer/T cell lymphoma nasal type simulating osteoradionecrosis with metachronic B lymphoma in the pelvis: Case report.

Extranodal Natural Killer/T Cell Lymphoma Nasal Type (EN-NK/T-CL-NT) is a non-Hodgkin extranodal lymphoma of unfavorable prognosis due to its aggressive nature. This neoplasm mainly affects the paranasal sinuses, nasopharynx, oropharynx, oral cavity, palate, and rarely intestinal, gastric and skin regions. 50-year-old female with a history of lymphoma in nasal and pelvic region. At four years of tumors-free, has facial asymmetry, accompanied by sub-palpebral, nasal and lip edema. Intraoral examination revealed a large ulceration suggestive of osteoradionecrosis. Gum biopsy shows Extranodal NK/T Cell Lymphoma Nasal Type (EN-NK/T-CL-NT). In this case we highlight the characteristics of EN-NK/T-CL-NT with a presentation of osteoradionecrosis-like. Unfortunately, the nature of this tumor led to the patient's death. Clinical follow-up of patients with cancer is imperative to mend and/or decrease treatment complications, as well as to identify second primary tumors or the spread of the underlying disease.

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来源期刊
CiteScore
1.20
自引率
0.00%
发文量
422
审稿时长
1 months
期刊介绍: The journal will cover studies related to pathology including morbid anatomy, surgical pathology, clinical pathology, diagnostic cytopathology including gynecologic cytology and aspiration cytology, hematology including immuno-hematology and medical microbiology. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed original research papers, case reports, systematic reviews, meta-analysis, letters to the editor and brief communications. Review articles on current topics usually are invited by the editor.
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