NUT midline carcinoma as a mediastinal tumor treated with cisplatin: A case report

NUT (nuclear protein of the testis) midline carcinoma (NMC) is a rare malignant and poorly differentiated squamous cell tumor that typically presents in midline structures of the head, neck and mediastinum with high degree of invasion and mortality, which occurs at any age, especially in teenagers and young people. We report a case of NMC presented as a mediastinal tumor. A 14-year-old female patient who presented with progressive dyspnea, cough with expectoration, and right pleural effusion and mediastinal space-occupying. Cisplatin (DDP)-based chemotherapy was performed. The prognosis is bad with an overall survival of 3 months.