疼痛,呻吟,呻吟的共同帮凶:棕色肿瘤的成像首次亮相

Meena Gl, M. Razak, Surbhi Gupta
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摘要

棕色肿瘤是局灶性骨病变,由破骨细胞活性增加和成纤维细胞增殖引起,常见于未控制的甲状旁腺功能亢进(HPT)患者。它们可以位于骨骼的任何部位,但最常发生在肋骨、锁骨、四肢和骨盆带。临床上重要的颅面骨病变是罕见的棕色肿瘤是由甲状旁腺功能亢进(HPT)引起的局灶性反应性溶骨性病变,代表甲状旁腺功能亢进依赖性骨病理的终末期。如今,甲状旁腺功能亢进的表现与这些病变是极为罕见的,在发达国家,因为早期发现疾病,采用常规实验室检查和早期治疗。棕色肿瘤是局灶性骨病变,由破骨细胞活性增加和成纤维细胞增殖引起,常见于不受控制的甲状旁腺功能亢进(HPT)患者。它们可以位于骨骼的任何部位,但最常发生在肋骨、锁骨、四肢和骨盆带。临床上重要的颅面骨病变是罕见的棕色肿瘤是由甲状旁腺功能亢进(HTP)引起的局灶性反应性溶骨性病变,代表甲状旁腺功能亢进依赖性骨病理的终末期。如今,甲状旁腺功能亢进的表现与这些病变是极为罕见的,在发达国家,因为早期发现疾病,采用常规实验室检查和早期治疗。这些良性病变表现出与骨转移相似的影像学表现,这使得诊断困难。
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The Common Accomplice of Pains, Moans, Groans: Imaging of Brown Tumors Debusted
Brown tumors are focal bone lesions, caused by increased osteoclastic activity and fibroblastic proliferation, encountered in patients with uncontrolled hyperparathyroidism (HPT). They can be located in any part of the skeleton, but are most frequently encountered in the ribs, clavicles, extremities, and pelvic girdle. Clinically significant lesions in the craniofacial bones are rare Brown tumors are focal reactive osteolytic lesions caused by hyperparathyroidism (HPT) and represent the terminal stage of the hyperparathyroidism-dependent bone pathology. Nowadays, the manifestation of hyperparathyroidism with these lesions is extremely rare in developed countries, because of the early detection of the disease, using routine laboratory examination and early treatment of that. These benign lesions present similar radiologic findings as bone metastasis, which makes the diagnosis difficult Brown tumors are focal bone lesions, caused by increased osteoclastic activity and fibroblastic proliferation, encountered in patients with uncontrolled hyperparathyroidism (HPT). They can be located in any part of the skeleton, but are most frequently encountered in the ribs, clavicles, extremities, and pelvic girdle. Clinically significant lesions in the craniofacial bones are rare Brown tumors are focal reactive osteolytic lesions caused by hyperparathyroidism (HTP) and represent the terminal stage of the hyperparathyroidism-dependent bone pathology. Nowadays, the manifestation of hyperparathyroidism with these lesions is extremely rare in developed countries, because of the early detection of the disease, using routine laboratory examination and early treatment of that. These benign lesions present similar radiologic findings as bone metastasis, which makes the diagnosis difficult.
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