四种驱蚊剂对冈比亚按蚊的驱蚊效果比较。

K. Ogillo, Lucille Lyaruu, E. Lyatuu, A. Mahande, E. Kweka
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摘要

个人防护工具在病媒传播疾病控制中至关重要。使用驱蚊剂是下床时使用的另一个工具。研究了避蚊胺(DEET)、麝香草(Maskitta)、柠檬草(lemon grass)和碳酸薄荷醇(Menthol propylene glycol carbonate, MR08) 4种驱蚊剂对疟媒冈比亚按蚊(Anopheles gambiae senso stricta)的防护效果。按甘油油的体积比配制避蚊胺(DEET)、马斯基塔(Maskitta)、香茅(Citronella)和MR08四种驱蚊剂。在30×30×30 cm笼中评估驱避剂对冈比亚按蚊的驱避剂量。志愿者接受治疗的手臂在笼子里暴露一小时,每次给药。消极控制也是如此。实验在温度为27±2℃,湿度为75±2%的室内进行。每个驱避实验设6个重复。本研究结果显示,马斯基塔的保护效果最高,避蚊胺次之,MR08和柠檬草的保护效果最差。本实验以避蚊胺为金标准阳性对照,甘油为阴性对照。Maskitta与避蚊胺的防护效率接近100%,而MRO8在所有浓度下的防护效率均在80%以上。从这些实验的结果来看,使用驱蚊剂作为个人防护装备在减少人类媒介接触方面具有重要作用。Maskitta是一种新研制的驱蚊剂,其防蚊效率为100%,这表明为了有更多优质有效的个人防蚊产品,还需要进行更多的科学研究。
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Comparative Efficiency of Four Repellents against Anopheles gambiae s.s.
Personal protection tools are of paramount importance in vector borne disease control. The use of repellents is an additional tool for use when out of bed. Four repellents N, N-Diethyl-3-methylbenzamide (DEET), Maskitta, lemon grass and Menthol propylene glycol carbonate (MR08) were examined in this experiment for their protective efficiency against malaria vectors Anopheles gambiae senso stricta. The four repellents DEET, Maskitta, Citronella and MR08 were formulated on volume based ratio against glycerin oil. The repellent dosages were evaluated against Anopheles gambiae in a 30×30×30 cm cage. Treated arm of a volunteer was exposed in the cage for a period of one hour for each dosage. Likewise for negative control. Experiments were conducted in a room with temperature and humidity of 27±2 degree Celsius and 75±2% respectively. Each repellent experiment had six replicates. In this study the results showed that, the protective efficiency was highest in Maskitta, followed by DEET, MR08 and lemon grass was least protective in all dosages. DEET was the golden standard positive control and glycerin was negative control in these experiments. Maskitta reached a protection efficiency of 100% similar to DEET while MRO8 were above 80% in all concentrations. From the results of these experiments, the use of repellents for personal protective gear has a significant role in reducing human-vector contact. Maskitta which is a newly formulated repellent showed a protection efficiency of 100%, this is evidence that more scientific research should be carried out in order to have more quality effective products for personal protection against mosquitoes.
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