老年慢性肾衰竭的实验室指标分析

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Acta Facultatis Medicae Naissensis Pub Date : 2022-01-01 DOI:10.5937/afmnai39-34954
E. Hasković, Harun Uzunalıć, S. Unčanin, S. Herenda, Denis Hasković, A. Selimović
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引用次数: 0

摘要

目的:本研究的主要目的是监测老年慢性肾衰竭患者的实验室参数。方法:所有样品均按标准方法和良好实验室操作规程进行处理。数据以有组织和系统的方式以道德原则问卷的形式收集,并通过统计检验和分析(学生t检验,方差-方差分析,Pearson和Spearman相关系数分析)进行分析。差异有统计学意义的极限为p < 0.05。结果:研究人群肌酐清除率和蛋白尿平均值分别为:41.30±21.43 mL/min、1.5±2.3 g/L/24 h。血液学参数与正常值无明显差异。共病发生率最高的是年龄≥80岁的受试者,平均每个受试者有2.03个共病。血清肌酐和尿素值以及肌酐清除率是疾病进展的良好指标。结论:本研究结果提示老年是慢性肾脏疾病发生的易感危险因素,并与合并症(高血压和/或糖尿病)合并,导致预后不良或疾病进展。
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An analysis of laboratory parameters of chronic kidney failure in elderly patients
Aim: The chief aim of this study was monitoring of laboratory parameters of chronic kidney failure in elderly patients. Methods: All samples were taken and processed by standard methods and according to the principles of good laboratory practice. Data were collected in an organized and systematic manner in the form of a questionnaire with respect to ethical principles and as such were analyzed by statistical tests and analyses (Student's t-test, Analysis of variance-ANOVA, Pearson's and Spearman's correlation coefficients). The limit of statistical significance was set at p < 0.05. Results: Mean values of creatinine clearance and proteinuria for the total study population were: 41.30 ± 21.43 mL/min, 1.5 ± 2.3 g/L/24 h, respectively. Hematological parameters did not significantly differ from normal values. The highest frequency of comorbidities was observed in subjects aged ≥ 80 years with an average of 2.03 comorbidities per subject. Serum creatinine and urea values as well as creatinine clearance are good indicators of disease progression. Conclusion: The results of the presented research suggest that old age is a predisposing risk factor for the development of chronic kidney disease, and that in combination with comorbidities (hypertension and/or diabetes), it contributes to poor prognosis or disease progression.
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来源期刊
Acta Facultatis Medicae Naissensis
Acta Facultatis Medicae Naissensis MEDICINE, GENERAL & INTERNAL-
CiteScore
0.70
自引率
0.00%
发文量
13
审稿时长
12 weeks
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