口服薰衣草提取物对退休中心退休人员高血压前期的影响:一项随机临床试验

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Acta Facultatis Medicae Naissensis Pub Date : 2022-01-01 DOI:10.5937/afmnai39-33837
Mahboobeh Ahmadabadi, F. Ghorat, Raha Salehabadi, Sedighe Rastaghi, M. Rad
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引用次数: 0

摘要

简介/目的:高血压是一种常见的老年疾病,可以通过草药来预防。本研究旨在评价薰衣草提取物对退休人群高血压前期的影响。方法:对60名退休男女进行三盲临床试验,采用排列阻滞技术将其分为薰衣草提取物组和安慰剂组。薰衣草提取物(源自花的部分)和安慰剂每天使用两次(每次3克相当于3毫升),持续两周。分别于用药前、用药后1周、2周及停药后1周测量血压,评价药物作用的稳定性。数据分析采用STATA软件14版,显著性水平p < 0.05。结果:干预前,薰衣草提取物组和安慰剂组的平均收缩压分别为133.9±9.3 mmHg和127.3±6.3 mmHg。干预1周后,各组平均血压分别为123.1±12.6 mmHg和125.8±7.2 mmHg,干预2周后分别为120.8±10.7 mmHg和127.9±2 mmHg。停药一周后,这些水平分别为123.7±10.7 mmHg和129.2±10.10 mmHg。重复测量方差分析结果显示,薰衣草提取物对干预组患者的收缩压和舒张压均有显著影响(p < 0.05)。结论:薰衣草提取物对退休人群高血压前期有明显的控制作用。
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Effect of the oral consumption of lavender extract (lavandula) on prehypertension in the retirees of retirement centers: A randomized clinical trial
Introduction/Aim: Hypertension is a common disorder of old age, which could be prevented by medicinal herbs. The present study aimed to evaluate the effect of lavender extract on prehypertension in the retired population. Methods: This triple-blind clinical trial was conducted on 60 retired men and women who were divided into two groups of lavender extract and placebo using the permuted block technique. Lavender extract (originating from flower part) and placebo were used twice a day (3 grams is equivalent to 3 cc each time) for two weeks. Blood pressure was measured before use, in the first and second week after use, and one week after the discontinuation of the medication to evaluate the stability of the drug effects. Data analysis was performed in STATA software version 14 at the significance level of p < 0.05. Results: Before the intervention, the mean systolic blood pressure in the lavender extract and placebo groups was 133.9 ± 9.3 mmHg and 127.3 ± 6.3 mmHg, respectively. After a one-week intervention, the mean blood pressure of the groups was 123.1 ± 12.6 mmHg and 125.8± 7.2 mmHg, respectively, while it was 120.8 ± 10.7 mmHg and 127.9 ± 2 mmHg after two weeks. One week after drug discontinuation, these levels were estimated at 123.7 ± 10.7 mmHg and 129.2 ± 10.10 mmHg, respectively. The results of repeated measures ANOVA indicated that lavender extract had significant effects on systolic and diastolic blood pressure in the intervention group (p < 0.05). Conclusion: According to the results, lavender extract was effective in prehypertension control in the retired subjects.
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来源期刊
Acta Facultatis Medicae Naissensis
Acta Facultatis Medicae Naissensis MEDICINE, GENERAL & INTERNAL-
CiteScore
0.70
自引率
0.00%
发文量
13
审稿时长
12 weeks
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