{"title":"几种香料对白化病大鼠生化指标的影响","authors":"N. E. O, Igbinobaro O.","doi":"10.5923/J.AJEE.20120201.02","DOIUrl":null,"url":null,"abstract":"The influences on the biochemical profiles by three medicinal plant parts used by pregnant women in the southern part of Nigeria, Tetrapleura tetraptera, Piper guineense, and Xylopia aethiopica were evaluated through a feeding study using Albino Whistar rats. The study revealed that extracts decreased the plasma cholesterol and triglyceride levels in treated rats and is attributable to the presence of hypolipidemic agent in the extracts. This shows that the extracts could reduce cardiovascular risk factor. Also, plasma levels of Potassium statistically decreased in the rats treated with T. tetraptera, P. guineense, and X. Aethiopica. This finding is suggestive of a hypokalaemic effect. Two major liver enzymes, ALT and AST plasma levels significantly decreased in the order X. Aethiopica > T. Tetraptera > P. Guineense and P. Guineense > X. Aethiopica > T. Tetraptera for ALT and AST respectively. These findings suggest effective potential to lower hepatotoxic effects by the spices.","PeriodicalId":92604,"journal":{"name":"American journal of environmental engineering","volume":"2 1","pages":"8-11"},"PeriodicalIF":0.0000,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"22","resultStr":"{\"title\":\"Effects of Some Selected Spices on Some Biochemical Profile of Wister Albino Rats\",\"authors\":\"N. E. O, Igbinobaro O.\",\"doi\":\"10.5923/J.AJEE.20120201.02\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The influences on the biochemical profiles by three medicinal plant parts used by pregnant women in the southern part of Nigeria, Tetrapleura tetraptera, Piper guineense, and Xylopia aethiopica were evaluated through a feeding study using Albino Whistar rats. The study revealed that extracts decreased the plasma cholesterol and triglyceride levels in treated rats and is attributable to the presence of hypolipidemic agent in the extracts. This shows that the extracts could reduce cardiovascular risk factor. Also, plasma levels of Potassium statistically decreased in the rats treated with T. tetraptera, P. guineense, and X. Aethiopica. This finding is suggestive of a hypokalaemic effect. Two major liver enzymes, ALT and AST plasma levels significantly decreased in the order X. Aethiopica > T. Tetraptera > P. Guineense and P. Guineense > X. Aethiopica > T. Tetraptera for ALT and AST respectively. These findings suggest effective potential to lower hepatotoxic effects by the spices.\",\"PeriodicalId\":92604,\"journal\":{\"name\":\"American journal of environmental engineering\",\"volume\":\"2 1\",\"pages\":\"8-11\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-08-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"22\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of environmental engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5923/J.AJEE.20120201.02\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of environmental engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5923/J.AJEE.20120201.02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 22
摘要
通过对白化惠斯鼠的饲养研究，评价了尼日利亚南部孕妇使用的三种药用植物四胸草(Tetrapleura tetratraptera)、几内亚胡椒(Piper guineense)和埃塞俄比亚木犀(Xylopia aethiopica)对生化指标的影响。研究表明，提取物降低了治疗大鼠血浆胆固醇和甘油三酯水平，这是由于提取物中存在降血脂剂。说明其提取物具有降低心血管危险因素的作用。此外，经四翅虫、几内亚弓形虫和埃塞俄比亚弓形虫治疗的大鼠血浆钾水平也有统计学上的下降。这一发现提示了低钾效应。血浆中两种主要肝酶ALT和AST水平分别显著降低了P. Aethiopica > T. Tetraptera > P. Guineense和P. Guineense > X. Aethiopica > T. Tetraptera。这些发现表明香料具有降低肝毒性作用的有效潜力。
Effects of Some Selected Spices on Some Biochemical Profile of Wister Albino Rats
The influences on the biochemical profiles by three medicinal plant parts used by pregnant women in the southern part of Nigeria, Tetrapleura tetraptera, Piper guineense, and Xylopia aethiopica were evaluated through a feeding study using Albino Whistar rats. The study revealed that extracts decreased the plasma cholesterol and triglyceride levels in treated rats and is attributable to the presence of hypolipidemic agent in the extracts. This shows that the extracts could reduce cardiovascular risk factor. Also, plasma levels of Potassium statistically decreased in the rats treated with T. tetraptera, P. guineense, and X. Aethiopica. This finding is suggestive of a hypokalaemic effect. Two major liver enzymes, ALT and AST plasma levels significantly decreased in the order X. Aethiopica > T. Tetraptera > P. Guineense and P. Guineense > X. Aethiopica > T. Tetraptera for ALT and AST respectively. These findings suggest effective potential to lower hepatotoxic effects by the spices.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
