药物终止妊娠后的心血管并发症:最新综述。

IF 1.9 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS World Journal of Cardiology Pub Date : 2023-10-26 DOI:10.4330/wjc.v15.i10.518
Tejveer Singh, Ajay K Mishra, Nikhil Vojjala, Kevin John John, Anu A George, Anil Jha, Michelle Hadley
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引用次数: 0

摘要

背景:在美利坚合众国,每年约有100万例药物终止妊娠(MTP),其中约2%的人出现并发症。MTP后或死产后发生的心血管(CVD)并发症没有得到很好的描述。目的:通过回顾MTP后出现的各种心脏合并症,帮助读者更好地理解、准备和管理这些并发症。方法:我们在PubMed、Medline、RCA和google scholar上进行了文献检索,使用搜索词“堕胎”或“医疗/法律终止妊娠”和“心脏并发症”或“心血管并发症”。结果:在MTP之后的文献中描述的最常见的并发症是感染性心内膜炎(IE)(n=16)、takotsubo心肌病(TTC)(n=7)、心律失常(n=5)和突然冠状动脉夹层(SCAD)(n=4)。IE中最常见的瓣膜是三尖瓣,占69%(n=10)。最常见的病原体是B组链球菌,占81%(n=12)。最常见的TTC类型为心尖型,占57%(n=4)。在五名出现心律失常的患者中,心动过缓最为常见,60%(3/5)的患者出现心动过缓。所有四例SCAD-P型病例在终止妊娠后10-14天均表现为急性冠状动脉综合征,主要累及右冠状动脉。IE后仅报告6.25%的死亡率。在所有这些并发症后进行最佳医疗管理后,临床恢复率持续报告。结论:总之,终止妊娠后心血管疾病并发症的发生在现有文献中很少记录。在这篇综述中,MTP后最常见的CVD并发症是IE和TTC。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Cardiovascular complications following medical termination of pregnancy: An updated review.

Background: Around 1 million cases of medical termination of pregnancy (MTP) take place yearly in the United States of America with around 2 percent of this population developing complications. The cardiovascular (CVD) complications occurring post MTP or after stillbirth is not very well described.

Aim: To help the reader better understand, prepare, and manage these complications by reviewing various cardiac comorbidities seen after MTP.

Methods: We performed a literature search in PubMed, Medline, RCA, and google scholar, using the search terms "abortions" or "medical/legal termination of pregnancy" and "cardiac complications" or "cardiovascular complications".

Results: The most common complications described in the literature following MTP were infective endocarditis (IE) (n = 16), takotsubo cardiomyopathy (TTC) (n = 7), arrhythmias (n = 5), and sudden coronary artery dissection (SCAD) (n = 4). The most common valve involved in IE was the tricuspid valve in 69% (n = 10). The most observed causative organism was group B Streptococcus in 81% (n = 12). The most common type of TTC was apical type in 57% (n = 4). Out of five patients developing arrhythmia, bradycardia was the most common and was seen in 60% (3/5) of the patients. All four cases of SCAD-P type presented as acute coronary syndrome 10-14 d post termination of pregnancy with predominant involvement of the right coronary artery. Mortality was only reported following IE in 6.25%. Clinical recovery was reported consistently after optimal medical management following all these complications.

Conclusion: In conclusion, the occurrence of CVD complications following pregnancy termination is infrequently documented in the existing literature. In this review, the most common CVD complication following MTP was noted to be IE and TTC.

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来源期刊
World Journal of Cardiology
World Journal of Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.30
自引率
5.30%
发文量
54
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