干细胞在血管重建后伤口愈合中的作用血管重建后愈合释放皮肤潜力。

Biao Cheng, Xiaobing Fu
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引用次数: 0

摘要

伤口愈合是一个复杂而动态的过程,涉及一系列细胞和分子事件。血运重建,即恢复缺血或受损组织的血流,是伤口愈合的关键步骤。充分的血管化已被认为是组织再生成功的必要因素。在伤口愈合的血运重建和组织重塑的后期,干细胞通过影响血管的成熟来调节其他修复细胞和基质的形成。还原氧化(REDOX)状态可能是通过干/祖细胞影响内皮细胞成熟血管和提高愈合质量的关键机制。线粒体可能在这一过程中发挥重要作用。
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The Role of Stem Cell on Wound Healing After Revascularization-Healing Following Revascularization-Unlocking Skin Potential.

Wound healing is a complex and dynamic process involving a series of cellular and molecular events. Revascularization, the restoration of blood flow to ischemic or damaged tissue, is a key step in wound healing. Adequate vascularization has been recognized as a necessary factor for successful tissue regeneration. In the later stage of revascularization and tissue remodeling in wound healing, stem cells regulate other repair cells and matrix formation by influencing the maturation of blood vessels. The reductive oxidation (REDOX) state may be a key mechanism through stem/progenitor cells to influence endothelial cells to mature blood vessels and improve the quality of healing. Mitochondria may play an important role in this process.

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