Ivan Nelinho Pérez-Maldonado, Carlos Gabriel De la Trinidad-Chacón, Amairani Lizbeth Perez-Lopez, Anette Aylin Perez-Lopez
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引用次数: 0
摘要
新兴的科学研究支持了这样一种假设,即暴露于环境化学物质会增加多种人类代谢紊乱的发生率。因此,本研究旨在评估墨西哥中部地区人群中氟暴露与代谢综合征(MetS)患病率之间的关系。这项研究包括575名成年个体。尿氟浓度采用电位法测定。还获得了人体测量和血压。测定血清空腹血糖和血脂水平。对于MetS筛查,我们使用了国际糖尿病联合会(IDF)和国家胆固醇教育计划成人治疗小组III(NCEP ATP III)标准。平均尿氟水平为3.50 ± 2.50 mg/L。根据NCEP ATP III和IDF标准,MetS的患病率分别约为27%和25%。多变量逻辑回归分析显示出显著的相关性(p
Association between urinary fluoride concentrations and the prevalence of metabolic syndrome in adult individuals from the Central Region of Mexico.
Emerging scientific studies have supported the hypothesis that exposure to environmental chemicals increases the incidence of diverse human metabolic disorders. Therefore, this study aimed to evaluate the association between fluoride exposure and metabolic syndrome (MetS) prevalence in people from the Central Region of Mexico. This research included 575 adult individuals. Urinary fluoride concentrations were determined using a potentiometric method. Anthropometric measurements and blood pressure were also acquired. Serum fasting glucose and lipid levels were quantified. For the MetS screening, we used the International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. The mean urinary fluoride levels were 3.50 ± 2.50 mg/L. The prevalence of MetS was approximately 27 and 25% according to NCEP ATP III and IDF criteria, respectively. A multivariate logistic regression analysis showed significant associations (p < 0.05) between urinary fluoride concentrations and MetS occurrence using NCEP ATP III criteria (OR = 1.60; 95% CI 1.05-2.10) and IDF criteria (OR = 1.35; 95% CI 0.95-1.45). These findings emphasize the need to discover the underlying mechanisms that fluoride exposure has on MetS pathogenesis.
期刊介绍:
International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.