{"title":"基于测序的单细胞多组学研究方法","authors":"Shanshan Qin, Songmei Liu, Xiaocheng Weng","doi":"10.1007/s11426-023-1793-7","DOIUrl":null,"url":null,"abstract":"<div><p>Single-cell multi-omics technologies have thrived in recent years. The combined studies of different modalities in single cells have enabled comprehensive insights into the complex functional networks of vital biomacromolecules, thus paving the way for a thorough understanding of cell biology and pathology. In this review, we focus on the advances of single-cell multi-omics technologies utilizing sequencing strategies and propose potential perspectives.\n</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"66 11","pages":"3024 - 3043"},"PeriodicalIF":10.4000,"publicationDate":"2023-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sequencing-based methods for single-cell multi-omics studies\",\"authors\":\"Shanshan Qin, Songmei Liu, Xiaocheng Weng\",\"doi\":\"10.1007/s11426-023-1793-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Single-cell multi-omics technologies have thrived in recent years. The combined studies of different modalities in single cells have enabled comprehensive insights into the complex functional networks of vital biomacromolecules, thus paving the way for a thorough understanding of cell biology and pathology. In this review, we focus on the advances of single-cell multi-omics technologies utilizing sequencing strategies and propose potential perspectives.\\n</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":772,\"journal\":{\"name\":\"Science China Chemistry\",\"volume\":\"66 11\",\"pages\":\"3024 - 3043\"},\"PeriodicalIF\":10.4000,\"publicationDate\":\"2023-10-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Science China Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11426-023-1793-7\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science China Chemistry","FirstCategoryId":"1","ListUrlMain":"https://link.springer.com/article/10.1007/s11426-023-1793-7","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Sequencing-based methods for single-cell multi-omics studies
Single-cell multi-omics technologies have thrived in recent years. The combined studies of different modalities in single cells have enabled comprehensive insights into the complex functional networks of vital biomacromolecules, thus paving the way for a thorough understanding of cell biology and pathology. In this review, we focus on the advances of single-cell multi-omics technologies utilizing sequencing strategies and propose potential perspectives.
期刊介绍：
Science China Chemistry, co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China and published by Science China Press, publishes high-quality original research in both basic and applied chemistry. Indexed by Science Citation Index, it is a premier academic journal in the field.
Categories of articles include:
Highlights. Brief summaries and scholarly comments on recent research achievements in any field of chemistry.
Perspectives. Concise reports on thelatest chemistry trends of interest to scientists worldwide, including discussions of research breakthroughs and interpretations of important science and funding policies.
Reviews. In-depth summaries of representative results and achievements of the past 5–10 years in selected topics based on or closely related to the research expertise of the authors, providing a thorough assessment of the significance, current status, and future research directions of the field.
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