随机试验中选择性参与的治疗效果鉴定

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2018-05-09 DOI:10.1111/ectj.12114
Brendan Kline, Elie Tamer
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引用次数: 2

摘要

随机试验(RT)用于了解治疗效果。本文研究了在各种假设下,从RT数据中识别平均治疗反应(ATR)和平均治疗效果(ATE)。重点是RT的外部有效性问题。由于RT的选择性参与,RT数据不需要对ATR或ATE进行点识别。本文报告了在各种假设下,基于RT数据对ATR和ATE的部分识别和点识别结果。结果包括足以从RT数据中点识别ATR或ATE的假设。在较弱的假设下,ATR或ATE被部分识别。此外,注意ATE的符号的识别和参与RT是否是选择性的识别。最后,将来自RT数据的识别与来自观测数据的识别进行比较。
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Identification of treatment effects with selective participation in a randomized trial

Randomized trials (RTs) are used to learn about treatment effects. This paper studies identification of average treatment response (ATR) and average treatment effect (ATE) from RT data under various assumptions. The focus is the problem of external validity of the RT. RT data need not point identify the ATR or ATE because of selective participation in the RT. The paper reports partial-identification and point-identification results for the ATR and ATE based on RT data under a variety of assumptions. The results include assumptions sufficient to point identify the ATR or ATE from RT data. Under weaker assumptions, the ATR or ATE is partially identified. Further, attention is given to identification of the sign of the ATE and identification of whether participation in the RT is selective. Finally, identification from RT data is compared to identification from observational data.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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