医源性和毒性动脉疾病

P. Cacoub (Professeur des Universités, praticien hospitalier), N. Limal (Chef de Clinique-assistant), J.-C. Piette (Professeur des Universités, praticien hospitalier)
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引用次数: 2

摘要

尽管并不罕见,但医源性和毒性动脉疾病在大多数情况下仍然诊断不足。已经报道了许多血管舒缩表现,如雷诺现象、活多、麦角病、红斑性皮肤痛和肢端发绀。阳性和病因诊断是基于病史,不需要进一步调查。在这篇综述中,我们描述了由麦角胺、β阻滞剂、抗肿瘤药物、钙通道阻滞剂和食欲抑制剂诱导的动脉疾病的主要特征。还综述了其他医源性非药物性动脉疾病,以及由专业毒物、可卡因或苯丙胺引起的医源性动脉疾病。
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Artériopathies iatrogènes et toxiques

Although not rare, iatrogenic and toxic arterial diseases remain, most of the time, underdiagnosed. Numerous vasomotor manifestations have been reported, such as Raynaud’s phenomenon, livedo, ergotism, erythermalgia, and acrocyanosis. Positive and etiologic diagnoses are based on the medical history and do not require further investigations. In this review, we describe main characteristics of those arterial diseases induced by ergotamine, beta-blocking agents, anti-neoplastic drugs, calcium channel blockers, and appetite-suppressant drugs. Other iatrogenic non-drug arterial diseases, and iatrogenic arteriopathies due to professional toxics, cocaine or amphetamines are also reviewed.

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