Isabel M. Ruiz-Hernández , Javier Gascó-Adrien , Carmen Buen-Ruiz , Laura Perelló-Moreno , Carmen Tornero-Prieto , Gonzalo Barrantes-Delgado , Mireia García-Gutiérrez , JM. Rapariz-González , S. Tejada-Gavela
{"title":"肉毒杆菌毒素A与富含血小板的血浆超声引导注射治疗足底筋膜炎：一项随机对照试验。","authors":"Isabel M. Ruiz-Hernández , Javier Gascó-Adrien , Carmen Buen-Ruiz , Laura Perelló-Moreno , Carmen Tornero-Prieto , Gonzalo Barrantes-Delgado , Mireia García-Gutiérrez , JM. Rapariz-González , S. Tejada-Gavela","doi":"10.1016/j.fas.2023.10.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p><span><span>Platelet-rich plasma (PRP) and botulinum toxin type A (BTX-A) injections have proven effective in </span>clinical trials for </span>plantar fasciitis<span><span> treatment but have not been directly compared. We aimed to compare clinical outcomes </span>in patients undergoing PRP or BTX-A injections.</span></p></div><div><h3>Methods</h3><p><span>We performed a randomised controlled trial<span> (59 patients; 1-year follow-up) to assess efficacy, using pain and functional scales (VAS, AOFAS Hindfoot-scale and FAAM questionnaire) and </span></span>fascia thickness reduction, in control and single ultrasound-guided BTX-A or PRP injection groups.</p></div><div><h3>Results</h3><p>The BTX-A group showed better results at 1-month after treatment. Conversely, the PRP injection was more effective in the long-term, with significant pain reduction and functional improvement. Plantar fascia thickness significantly reduced from months 1 and 3 in the PRP and BTX-A groups, respectively.</p></div><div><h3>Conclusion</h3><p>PRP and BTX-A injections are effective in patients with plantar fasciitis with BTX-A achieving better short-term pain reduction and PRP better long-term results.</p></div><div><h3>Level of Evidence</h3><p><strong>Level</strong> I; Randomised Controlled Trial</p></div>","PeriodicalId":48743,"journal":{"name":"Foot and Ankle Surgery","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Botulinum toxin A versus platelet rich plasma ultrasound-guided injection in the treatment of plantar fasciitis: A randomised controlled trial\",\"authors\":\"Isabel M. Ruiz-Hernández , Javier Gascó-Adrien , Carmen Buen-Ruiz , Laura Perelló-Moreno , Carmen Tornero-Prieto , Gonzalo Barrantes-Delgado , Mireia García-Gutiérrez , JM. Rapariz-González , S. Tejada-Gavela\",\"doi\":\"10.1016/j.fas.2023.10.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p><span><span>Platelet-rich plasma (PRP) and botulinum toxin type A (BTX-A) injections have proven effective in </span>clinical trials for </span>plantar fasciitis<span><span> treatment but have not been directly compared. We aimed to compare clinical outcomes </span>in patients undergoing PRP or BTX-A injections.</span></p></div><div><h3>Methods</h3><p><span>We performed a randomised controlled trial<span> (59 patients; 1-year follow-up) to assess efficacy, using pain and functional scales (VAS, AOFAS Hindfoot-scale and FAAM questionnaire) and </span></span>fascia thickness reduction, in control and single ultrasound-guided BTX-A or PRP injection groups.</p></div><div><h3>Results</h3><p>The BTX-A group showed better results at 1-month after treatment. Conversely, the PRP injection was more effective in the long-term, with significant pain reduction and functional improvement. Plantar fascia thickness significantly reduced from months 1 and 3 in the PRP and BTX-A groups, respectively.</p></div><div><h3>Conclusion</h3><p>PRP and BTX-A injections are effective in patients with plantar fasciitis with BTX-A achieving better short-term pain reduction and PRP better long-term results.</p></div><div><h3>Level of Evidence</h3><p><strong>Level</strong> I; Randomised Controlled Trial</p></div>\",\"PeriodicalId\":48743,\"journal\":{\"name\":\"Foot and Ankle Surgery\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Foot and Ankle Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1268773123001923\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Foot and Ankle Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1268773123001923","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Botulinum toxin A versus platelet rich plasma ultrasound-guided injection in the treatment of plantar fasciitis: A randomised controlled trial
Background
Platelet-rich plasma (PRP) and botulinum toxin type A (BTX-A) injections have proven effective in clinical trials for plantar fasciitis treatment but have not been directly compared. We aimed to compare clinical outcomes in patients undergoing PRP or BTX-A injections.
Methods
We performed a randomised controlled trial (59 patients; 1-year follow-up) to assess efficacy, using pain and functional scales (VAS, AOFAS Hindfoot-scale and FAAM questionnaire) and fascia thickness reduction, in control and single ultrasound-guided BTX-A or PRP injection groups.
Results
The BTX-A group showed better results at 1-month after treatment. Conversely, the PRP injection was more effective in the long-term, with significant pain reduction and functional improvement. Plantar fascia thickness significantly reduced from months 1 and 3 in the PRP and BTX-A groups, respectively.
Conclusion
PRP and BTX-A injections are effective in patients with plantar fasciitis with BTX-A achieving better short-term pain reduction and PRP better long-term results.
期刊介绍：
Foot and Ankle Surgery is essential reading for everyone interested in the foot and ankle and its disorders. The approach is broad and includes all aspects of the subject from basic science to clinical management. Problems of both children and adults are included, as is trauma and chronic disease. Foot and Ankle Surgery is the official journal of European Foot and Ankle Society.
The aims of this journal are to promote the art and science of ankle and foot surgery, to publish peer-reviewed research articles, to provide regular reviews by acknowledged experts on common problems, and to provide a forum for discussion with letters to the Editors. Reviews of books are also published. Papers are invited for possible publication in Foot and Ankle Surgery on the understanding that the material has not been published elsewhere or accepted for publication in another journal and does not infringe prior copyright.
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