5-氨基乙酰丙酸光动力疗法治疗难治性严重溃疡1例报告。

Photodiagnosis and photodynamic therapy Pub Date : 2023-12-01 Epub Date: 2023-11-09 DOI:10.1016/j.pdpdt.2023.103888
Feng Li, Jia He, Ting Yang, Si Li, Li Liu, Qing Huang, Xi Duan
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引用次数: 0

摘要

Kerion是头癣的一种亚型,具有严重的炎症反应,需要早期诊断以防止继发性细菌感染、毛囊炎和永久性脱发。口服抗真菌药物被认为是治疗头癣的一线药物;然而,药物治疗受到治疗时间长、副作用和耐药性的挑战。光动力疗法(PDT)已被广泛用于治疗皮肤真菌病,近年来已显示出显著的疗效。我们报告了一例女孩,她在不规范的治疗和对伊曲康唑不敏感后出现难治性严重溃疡;然而,她用5-氨基乙酰丙酸PDT治愈了。该病例表明,PDT是治疗皮肤真菌感染的一种潜在的有前景的替代疗法。
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5-aminolevulinic acid-photodynamic therapy for a refractory severe kerion: A case report.

Kerion is a subtype of tinea capitis with a severe inflammatory response, requiring early diagnosis to prevent secondary bacterial infection, folliculitis and permanent alopecia. Oral antifungal drugs are considered the first-line treatment for tinea capitis; however, drugs therapy is challenged by the long treatment duration, side effects, and drug resistance. Photodynamic therapy (PDT) has been widely used to treat dermatomycosis and has shown significant efficacy in recent years. We report the case of a girl who presented with refractory severe kerion following unregulated treatment and insensitivity to itraconazole; however,she was cured with 5-aminolevulinic acid-PDT. The case showed that PDT is a potentially promising alternative treatment for cutaneous fungal infections.

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