沃罗涅日地区中药材原料元素组成测定

N. Dyakova
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Pharmacopoeic types of medicinal vegetal raw materials were used as subjects of investigation: nettle leaves dioecious (Urtica dioica L.), plantain leaves large (Plantago major L.), common pajma flowers (Tanacetum vulgare L.), heart-shaped linden flowers (Tilia cordata Mill.), herb of five-lobed dumplings (Leonurus quinquelobatus Gilib.), grass of bitter wormwood (Artemisia absinthium L.), common millennium grass (Achillea millefolium L.), bird mountain grass (Polygonum aviculare L.), roots of the common bladder (Arctium lappa L.), roots of the dandelion drug (Taraxacum officinale F.H. Wigg). Raw material harvesting was carried out in accordance with pharmacopoeic rules in natural thickets in the Voronezh State Natural Biosphere Reserve named after V. M. Peskov in the Ramonsky district. The microelement composition of the samples was studied mass-spectroscopically on an ELAN DRC device (PerkinElmer Instruments, USA) after acid-microwave decomposition.Results and discussion. In each plant sample, 59 elements were quantified. The content of the total elemental complex in the studied types of LRs varies from 1.91 to 7.68 % in terms of dry raw materials. The studied raw materials accumulate macroelements to the greatest extent (more than 84 %). Essential trace elements accumulate most in dioecious nettle leaves (more than 9 mg/g). Of the essential trace elements, silicon and iron accumulate most of all the studied raw materials. Content of regulated toxic trace elements does not exceed requirements of pharmacopoeia.Conclusion. The results of the study showed a complex macro- and microelement composition of the studied medicinal vegetal raw materials, which can be used in the medical and pharmaceutical practice of creating phytopreparations and biologically active additives for correcting physiological norms of the content of elements in the human body. 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The available information on the elemental composition of medicinal plant raw materials of the Voronezh region showed that studies are carried out mainly on several elements, which does not allow determining the complete mineral complex of medicinal plants and describing the specifics of the accumulation of individual elements in them.Aim. The purpose of the study is to study the macro- and microelement composition of medicinal plant raw materials of the Voronezh region on the example of a protected area.Materials and methods. 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In each plant sample, 59 elements were quantified. The content of the total elemental complex in the studied types of LRs varies from 1.91 to 7.68 % in terms of dry raw materials. The studied raw materials accumulate macroelements to the greatest extent (more than 84 %). Essential trace elements accumulate most in dioecious nettle leaves (more than 9 mg/g). Of the essential trace elements, silicon and iron accumulate most of all the studied raw materials. Content of regulated toxic trace elements does not exceed requirements of pharmacopoeia.Conclusion. The results of the study showed a complex macro- and microelement composition of the studied medicinal vegetal raw materials, which can be used in the medical and pharmaceutical practice of creating phytopreparations and biologically active additives for correcting physiological norms of the content of elements in the human body. 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引用次数: 0

摘要

介绍。关于沃罗涅日地区药用植物原料元素组成的现有信息表明,研究主要是对几种元素进行的,这无法确定药用植物的完整矿物复合物和描述单个元素在其中积累的具体情况。本研究的目的是研究沃罗涅日地区药用植物原料的宏量和微量元素组成,以保护区为例。材料和方法。以药用植物原料的药典类型为调查对象:荨麻雌雄异株叶(Urtica dioica L.),大车前草叶(Plantago major L.),普通睡莲花(Tanacetum vulgare L.),心形菩提树花(Tilia cordata Mill.),五叶水草(Leonurus quinquelobatus Gilib.),苦艾草(Artemisia absinthium L.),普通千禧年草(Achillea millefolium L.),鸟山草(Polygonum aviculare L.),普通尿片根(牛蒡根),蒲公英药物(Taraxacum officinale F.H. Wigg)的根。根据药典规则,在以V. M. Peskov命名的沃罗涅日国家自然生物圈保护区的自然灌木丛中进行原料采收。样品经酸微波分解后,在ELAN DRC (PerkinElmer Instruments, USA)上进行质谱分析。结果和讨论。每个植物样品中有59个元素被定量。在所研究的LRs中,总元素配合物的含量在1.91 ~ 7.68%之间。所研究的原料中微量元素的富集程度最大(超过84%)。必需微量元素在雌雄异株荨麻叶片中积累最多(大于9 mg/g)。在必需微量元素中,硅和铁在所有研究的原料中积累最多。规定的有毒微量元素含量未超过药典要求。研究结果表明,所研究的药用植物原料具有复杂的宏量和微量元素组成,可用于医学和制药实践中创造植物修复剂和生物活性添加剂,以纠正人体元素含量的生理规范。以五叶饺子的草、雌雄异株的荨麻叶和大车前草的元素组成最丰富(大于50 mg/g)。
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Examination of Elemental Composition of Herbal Medicinal Raw Materials of Voronezh Region
Introduction. The available information on the elemental composition of medicinal plant raw materials of the Voronezh region showed that studies are carried out mainly on several elements, which does not allow determining the complete mineral complex of medicinal plants and describing the specifics of the accumulation of individual elements in them.Aim. The purpose of the study is to study the macro- and microelement composition of medicinal plant raw materials of the Voronezh region on the example of a protected area.Materials and methods. Pharmacopoeic types of medicinal vegetal raw materials were used as subjects of investigation: nettle leaves dioecious (Urtica dioica L.), plantain leaves large (Plantago major L.), common pajma flowers (Tanacetum vulgare L.), heart-shaped linden flowers (Tilia cordata Mill.), herb of five-lobed dumplings (Leonurus quinquelobatus Gilib.), grass of bitter wormwood (Artemisia absinthium L.), common millennium grass (Achillea millefolium L.), bird mountain grass (Polygonum aviculare L.), roots of the common bladder (Arctium lappa L.), roots of the dandelion drug (Taraxacum officinale F.H. Wigg). Raw material harvesting was carried out in accordance with pharmacopoeic rules in natural thickets in the Voronezh State Natural Biosphere Reserve named after V. M. Peskov in the Ramonsky district. The microelement composition of the samples was studied mass-spectroscopically on an ELAN DRC device (PerkinElmer Instruments, USA) after acid-microwave decomposition.Results and discussion. In each plant sample, 59 elements were quantified. The content of the total elemental complex in the studied types of LRs varies from 1.91 to 7.68 % in terms of dry raw materials. The studied raw materials accumulate macroelements to the greatest extent (more than 84 %). Essential trace elements accumulate most in dioecious nettle leaves (more than 9 mg/g). Of the essential trace elements, silicon and iron accumulate most of all the studied raw materials. Content of regulated toxic trace elements does not exceed requirements of pharmacopoeia.Conclusion. The results of the study showed a complex macro- and microelement composition of the studied medicinal vegetal raw materials, which can be used in the medical and pharmaceutical practice of creating phytopreparations and biologically active additives for correcting physiological norms of the content of elements in the human body. The most quantitatively rich elemental composition is noted for the grass of five-lobed dumplings, nettle leaves of dioecious and large plantain (more than 50 mg/g).  
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