用太赫兹化学显微镜用免疫反应检测癌细胞

Y. Yoshida, X. Ding, K. Iwatsuki, H. Inoue, J. Wang, K. Sakai, T. Kiwa
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引用次数: 0

摘要

最近,分析癌症基因组被吸引到个性化癌症治疗中。标本中癌细胞的比例对于基因组的精确分析至关重要。我们小组提出并开发了一种太赫兹化学显微镜(TCM)来测量溶液中癌细胞的数量。本研究利用亲和素-生物素反应将生物素标记的AE1/AE3固定在传感板上,成功检测了溶液中的肺癌细胞。
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Detection of cancer cells using immune reaction with a terahertz chemical microscope
Recently, analyzing cancer genome is attracted to personalize cancer treatment. The ratio of cancer cells in a specimen is essential for precise analysis of the genome. In our group, a terahertz chemical microscope (TCM) has been proposed and developed to measure the number of cancer cells in solution. In this study, a biotin-tagged AE1/AE3 was immobilized on a sensing plate using avidin-biotin reaction, and we succeed in detecting lung cancer cells in solutions.
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