免疫系统可以靶向治疗COVID-19吗?

Sarah Abdelhafeez, D. Doherty
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引用次数: 0

摘要

在COVID-19中,SARS-CoV-2已被证明可以激活先天和适应性免疫反应。然而,不受控制或受损的免疫可导致疾病的严重形式的发展。了解影响疾病表达的潜在免疫学以及病毒的自然历史对于制定预防和治疗策略以应对COVID-19大流行至关重要。本章旨在讨论临床背景下关于COVID-19免疫学的文献,特别是应用于SARS-CoV-2治疗方法和疫苗的开发。版权所有©ERS 2021。
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Can the immune system be targeted to treat COVID-19?
In COVID-19, SARS-CoV-2 has been shown to activate both innate and adaptive immune responses. However, uncontrolled or impaired immunity can lead to the development of severe forms of the disease. Understanding the underlying immunology influencing disease expression as well as the natural history of the virus is imperative to develop preventative and therapeutic strategies to tackle the COVID-19 pandemic. This chapter aims to discuss the literature surrounding the immunology of COVID-19 in a clinical context, specifically applied to the development of therapeutics and vaccines to SARS-CoV-2.Copyright © ERS 2021.
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