采用区域分解和优先队列积分方案求解二维心肌模型

W. Quan, S. Evans, H. Hastings
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引用次数: 2

摘要

基于Luo-Rudy相膜模型的二维传播模型由于计算量大而受到限制。为了降低这一成本并允许大型的真实模型,作者提出了一种新的基于区域分解和优先队列集成方案(DDPQ)的数值方法。新方法提供了稳定的解决方案,相对误差小于1%,计算时间节省了10到20倍,允许基于真实膜动力学和真实尺寸的更大模型来模拟再入,触发活动及其相互作用。
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Using domain decomposition and priority queue integration scheme to solve two-dimensional model of myocardium
The two-dimensional propagation model based on the Luo-Rudy phase II membrane model is limited by its great computational cost. To reduce this cost and allow large realistic models the authors developed a new numerical method based on domain decomposition and priority queue integration scheme (DDPQ). The new method offers stable solutions with relative errors less than 1% and computation time saving by a factor of 10 to 20, allowing much larger models based on realistic membrane kinetics and realistic dimensions to simulate reentry, triggered activity and their interactions.
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