来自印度特伦加纳邦的药用植物卷叶草(Linn.f.)内生真菌的抗菌活性研究。

A. Aruna, M. Abhinesh, V. Bhavani, V. K. Reddy
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引用次数: 1

摘要

收稿日期:2019年1月23日,收稿日期:2019年2月10日,在线日期:2019年2月28日摘要─内生真菌可以产生多种具有药理意义的代谢物。与药用植物相关的内生菌是深入研究的目标。本研究研究了一种传统药用植物——水仙(Wattakaka volubili)的内生真菌。共分离到39种真菌,其中大部分为不完全真菌。同一寄主的地理和环境条件不同,真菌种类也不同。在不同属中,曲霉属、青霉属、镰刀菌属、真菌属和无菌菌丝属占优势。对5种内生真菌(米曲霉、红豆双plodia andamanensis、禾谷镰刀菌、红青霉和bataticola Rhizoctonia)的溶剂提取物进行了对4种人类致病菌的抑菌活性试验,结果表明,不同溶剂和真菌的抑菌活性不同。对大肠杆菌的抑制作用非常明显。己醇和氯仿提取物的活性与链霉素非常接近。根据这些观察结果,建议需要进一步测试纯提取物的抗菌活性。
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Antibacterial Activity of Fungal Endophytes Isolated from Wattakaka volubilis (Linn.f.), A medicinal plant from Telangana, India.
Received: 23/Jan/2019, Accepted: 10/Feb/2019, Online: 28/Feb/2019 Abstract─ Endophytic fungi are known to produce a wide range of metabolites of pharmacological importance. Endophytes associated with medicinal plants are targets for intensive research. This research paper deals with the endophytic fungi isolated from Wattakaka volubili also known as Dudipala, a high valued medicinal plant in traditional medicine. A total of 39 fungal species representing mostly imperfect fungi were isolated from different plant parts. The fungal species varied with geographic and environmental conditions of the same host species. Among different genera, Aspergillus, Penicillium, Fusarium, Phoma and mycelia sterilia were dominant. Solvent extracts of five endophytic fungi viz Aspergillus oryzae, Diplodia andamanensis, Fusarium graminearum, Penicillium rubrum and Rhizoctonia bataticola were tested against four human pathogenic bacteria, Antibacterial activity varied with the fungus as well as solvent. The inhibitory activity is very prominent on E.coli. Hexanol and chloroform extracts activity is very close to streptomycin. In light of these observations it is recommended that the pure extracts need to further test for antibacterial activity.
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