【功能性高雄激素症——分类、病因、诊断和治疗】。

F. Geisthövel
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引用次数: 3

摘要

本文提出的功能性高雄激素症(FHA)的分类是基于已知的临床经验和最新的分子生物学数据。功能性高雄激素症由各种器官系统特异性实体组成,因此具有不同的诊断和治疗策略。多囊卵巢综合征(PCOS)一词具有误导性,应以适当的描述代替。尽管在分子生物学方面进行了激烈的讨论并取得了进展,但此处描述的FHA iii组除外,其病因学后果在诊断和治疗程序方面尚未解决。基于人类基因组遗传筛选方法(微阵列)的最新发现,可能在不久的将来可以更好地了解潜在的病理生理。
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[Functional hyperandrogenism--classification, etiology, diagnosis and therapy].
The classification of functional hyperandrogenism (FHA) presented in this paper is based on well known clinical experience supported by recent data of molecular biology. Functional hyperandrogenism is composed of various organ system-specific entities with consequently differential diagnostic and therapeutic strategies. The term polycystic ovary syndromes (PCOS) is misleading and should be replaced by adequate descriptions. Inspite of intense discussions and progress in molecular biology are with the exception of the here described FHA III-group the etiological consequences unresolved in terms of diagnostic and therapeutic procedures. Based on recent findings on the human genome genetic screening methods (Microarrays) may be available in the near future to allow a better understanding of the underlying pathophysiology.
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