T. J. Norman, D. Parker, L. Royle, A. Harrison, Pari Antoniwb, David J. Kingb
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Improved tumour targeting with recombinant antibody–macrocycle conjugates
Linkage of a macrocyclic complexing agent to a spaced tri-maleimide allows formation of a recombinant trivalent antibody by reaction with a Δ-Cys Fab fragment of an engineered human antibody.