betalain在实用医学中

V. M. Koldaev, A. Kropotov, O. Li
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引用次数: 0

摘要

甜菜素是在石竹类植物(红甜菜、菊苣等)的细胞中合成的植物色素。它们参与活性氧和自由基的失活。本文综述了甜菜碱的理化性质和药理研究进展。Betalains消除氧化应激的后果,有效纠正糖尿病和腹部肥胖的代谢紊乱,并降低心血管疾病的风险。富含甜菜素的饮食具有广泛的抗癌作用。Betalains保护大脑多巴胺能神经元免受氧化损伤,降低阿尔茨海默病和帕金森病神经退行性疾病的严重程度。然而,甜菜碱在植物原料的加工和储存过程中不够稳定,无法抵抗降解。因此,开发非破坏性的含β素治疗技术是非常重要的。
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Betalains in practical medicine
Betalains are plant pigments synthesized in the cells of Caryophyllales (red beets, opuntia, etc.). They are involved in the inactivation of reactive oxygen species and free radicals. The paper summarizes the data on the physical-chemical and pharmacological properties of betalains. Betalains eliminate the consequences of oxidative stress, effectively correct metabolic disorders in diabetes mellitus and abdominal obesity, and reduce the risk of cardiovascular diseases. A betalain-enriched diet has a wide range of anticancer effects. Betalains protect brain dopaminergic neurons from oxidative damage and reduce the severity of neurodegenerative disorders in Alzheimer’s and Parkinson’s disease. However, betalains are not stable enough to resist degradation during processing and storage of plant raw materials. Therefore, developing non-damaging technologies for betalain-containing treatment is highly relevant.
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