Cryptogenic organising pneumonia- Atypical presentation

Organizing pneumonia is an interstitial lung disease that affects the distal bronchiole, respiratory bronchiole, alveolar ducts, and walls. To diagnose cryptogenic organising pneumonia, other aetiologies, such as inflammatory infections, connective tissue disease, drug responses, pulmonary infarction, and organ transplantation need to be ruled out. Radiological and histological progress in this disease will help to understand the disease in a better way. Early diagnosis of organizing pneumonia is important because of a good prognosis if it is treated earlier. But atypical clinical and radiological presentation will lead to difficulty in diagnosis and delay in treatment. Here we report two atypical presentations of organizing pneumonia cases to highlight the importance of upfront aggressive multimodality diagnostic approaches to rule out rare causes of cavitating lesions.