脂肪组织的调色板:多种功能和非凡的可塑性

J. Pauli
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引用次数: 1

摘要

在认识了脂肪组织作为内分泌器官和调节代谢的作用后,对其生物学功能的研究也有了新的进展。以前,在哺乳动物中只鉴定出两种脂肪组织,白色脂肪组织和棕色脂肪组织。白色脂肪细胞主要储存脂质,具有能量储备功能,棕色脂肪细胞主要保持热稳态。由于脂肪组织的可塑性及其增殖和分化的能力,出现了第三种类型的脂肪细胞,米黄色。米色脂肪细胞起源于白色脂肪细胞,在不同的刺激下获得了表型上的棕色特征,这一过程被称为褐变。最近,塑料特性使得第四种脂肪组织——粉色脂肪组织得以识别。
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A Palette of Adipose Tissue: Multiple Functionality and Extraordinary Plasticity
After the knowledge of adipose tissue as an endocrine organ and its role as a regulator of metabolisms, studies have advanced on its biological function. Previously, only two adipose tissues were identified in mammals, white and brown adipose tissue. White adipocytes store lipids mainly with the function of energy reserve and brown for thermal homeostasis. Due to the plasticity of adipose tissue and its ability to proliferate and differentiate, the third type of adipocyte, beige, emerged. Beige adipocytes originate from white adipocytes that have acquired phenotypic brown characteristics in response to different stimuli, this process is known as browning. More recently, the plastic properties allowed the identification of the fourth type of adipose tissue, the pink.
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