口腔扁平地衣切口活检标本中出现粪体

A. Sanches, Alessandra Laís Pinho Valente Pires, T. C. F. Ramos, Beatriz de Araújo Frota, Hortencia Resende dos Santos DELLA CELLA, M. Oliveira, V. S. Freitas, G. B. Martins
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引用次数: 0

摘要

【摘要】目的:Civatte小体是位于真皮表皮交界处的角质形成细胞凋亡的胶体小体,常见于包括扁平苔藓病变在内的几种皮肤病。本研究旨在确定从诊断为口腔扁平苔藓的患者获得的切口活检样本中是否存在Civatte小体。方法:回顾性横断面研究,采用34张苏木精-伊红染色的载玻片,这些载玻片来自某高等教育机构口腔病理实验室的档案。根据现有的临床资料,将获得的样本分为白色和红色病变。在光镜下进行组织学分析,10倍和40倍的物镜,确定是否存在Civatte体。结果:总样本中有73.5%存在胶体体,白色病变中有74.2%存在胶体体。结论:鼠体在所有标本中都很常见,应作为口腔扁平苔藓病变的组织学诊断标准。
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Presence of Civatte Bodies in an oral lichen planus incisional biopsy sample
ABSTRACT Objective: Civatte bodies are colloid bodies of apoptotic keratinocytes located at the dermoepidermal junction and are common in several dermatoses, including lichen planus lesions. The present study aimed to determine the presence of Civatte bodies in a sample of incisional biopsies obtained from patients diagnosed with oral lichen planus. Methods: A retrospective cross-sectional study, carried out with 34 slides stained with hematoxylin-eosin from the archive of an Oral Pathology Laboratory of a Higher Education Institution. The sample obtained was classified into white and red lesions from the available clinical data. Histological analyses were performed under a light microscope, with 10x and 40x objectives, identifying the presence or absence of Civatte bodies. Results: Colloid bodies were present in 73.5% the total sample studied and in 74.2% white lesions. Conclusion: The Civatte bodies were frequent in all samples analysed and should thus be considered a criterion for histological diagnosis in lesions of Oral Lichen Planus.
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审稿时长
20 weeks
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