长非编码 RNA 在肝细胞癌中的表达和功能

Cancer Innovation Pub Date : 2023-08-15 DOI:10.1002/cai2.90
Jingli Du, Yue Su, Jianzhi Gao, Yanhong Tai
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引用次数: 0

摘要

随着基因组计划研究的深入,非编码 RNA 越来越受到关注。长非编码 RNA(lncRNA)已成为一个新的研究热点。越来越多的研究发现,lncRNAs 参与了肿瘤发生和肿瘤抑制通路。在包括肝细胞癌(HCC)在内的多种人类肿瘤中都发现了lncRNAs的异常表达。在这篇综述中,我们简要介绍了lncRNA,并重点介绍了最近关于lncRNA在HCC中的功能和临床意义的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The expression and function of long noncoding RNAs in hepatocellular carcinoma

With the deepening of the genome project study, attention on noncoding RNAs is increasing. Long noncoding RNAs (lncRNAs) have become a new research hotspot. A growing number of studies have revealed that lncRNAs are involved in tumorigenesis and tumor suppressor pathways. Aberrant expressions of lncRNAs have been found in a variety of human tumors including hepatocellular carcinoma (HCC). In this review, we provide a brief introduction to lncRNA and highlight recent research on the functions and clinical significance of lncRNAs in HCC.

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