综述了卡托普利胃保留漂浮片的天然高分子材料与合成高分子材料,并比较了高分子材料的疗效

S. Chauhan
{"title":"综述了卡托普利胃保留漂浮片的天然高分子材料与合成高分子材料,并比较了高分子材料的疗效","authors":"S. Chauhan","doi":"10.20959/WJPR201711-9561","DOIUrl":null,"url":null,"abstract":"The oral route of drug administration is the most important method of administering drug for systematic effect. The present study was undertaken to prolong the release of orally administer. Captopril in the floating tablets by using different grade of HPMC. Formulation were optimized using different viscosity grades of HPMC. Lactose and citric acid and also natural polymers chitosan and carbopole. were used in different concentration as a channeling and chelating agent to obtain best optimized formulation and designed to prolong the gastric residence time (GRT). KEYWORD: gastroretentive floating drung delivery system, Gastric retention time, HPMC, Lactose, Carbopole, Chitosan.","PeriodicalId":23796,"journal":{"name":"World journal of pharmaceutical research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A COMPREHENSIVE REVIEW ON GASTRORETENTIVE FLOATING TABLET OF CAPTOPRIL USING NATURAL AND SYNTHETIC POLYMER WITH COMPARISION OF POLYMER EFFICACY\",\"authors\":\"S. Chauhan\",\"doi\":\"10.20959/WJPR201711-9561\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The oral route of drug administration is the most important method of administering drug for systematic effect. The present study was undertaken to prolong the release of orally administer. Captopril in the floating tablets by using different grade of HPMC. Formulation were optimized using different viscosity grades of HPMC. Lactose and citric acid and also natural polymers chitosan and carbopole. were used in different concentration as a channeling and chelating agent to obtain best optimized formulation and designed to prolong the gastric residence time (GRT). KEYWORD: gastroretentive floating drung delivery system, Gastric retention time, HPMC, Lactose, Carbopole, Chitosan.\",\"PeriodicalId\":23796,\"journal\":{\"name\":\"World journal of pharmaceutical research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World journal of pharmaceutical research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.20959/WJPR201711-9561\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World journal of pharmaceutical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20959/WJPR201711-9561","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

口服给药途径是最重要的给药方式。本研究是为了延长口服给药的释放。用不同等级的HPMC对卡托普利进行浮片试验。采用不同粘度等级的HPMC对配方进行优化。乳糖和柠檬酸以及天然聚合物壳聚糖和卡波酮。以不同浓度作为通道和螯合剂,获得最佳优化配方,旨在延长胃停留时间(GRT)。关键词:胃保留漂浮药物给药系统,胃保留时间,HPMC,乳糖,卡波波尔,壳聚糖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
A COMPREHENSIVE REVIEW ON GASTRORETENTIVE FLOATING TABLET OF CAPTOPRIL USING NATURAL AND SYNTHETIC POLYMER WITH COMPARISION OF POLYMER EFFICACY
The oral route of drug administration is the most important method of administering drug for systematic effect. The present study was undertaken to prolong the release of orally administer. Captopril in the floating tablets by using different grade of HPMC. Formulation were optimized using different viscosity grades of HPMC. Lactose and citric acid and also natural polymers chitosan and carbopole. were used in different concentration as a channeling and chelating agent to obtain best optimized formulation and designed to prolong the gastric residence time (GRT). KEYWORD: gastroretentive floating drung delivery system, Gastric retention time, HPMC, Lactose, Carbopole, Chitosan.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Effect of caffeine on the acceptability of novel flavoured drinks. FORMULATION AND DEVELOPMENT OF FLURBIPROFEN CONTAINING FILM FORMING GEL EVALUATION OF CLINICAL EFFICACY OF GANDHAKAKALPA IN VICHARCHIKA A COMPREHENSIVE REVIEW ON GASTRORETENTIVE FLOATING TABLET OF CAPTOPRIL USING NATURAL AND SYNTHETIC POLYMER WITH COMPARISION OF POLYMER EFFICACY IN- SITU NASAL GEL: MODERNISTIC ADVANCEMENT IN DRUG DELIVERY
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1