环草不同提取物及组分的植物药理学研究

R. Poonghuzhali, S. Samraj, A. Nisha, S. N. Nair, M. Priya
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摘要

青环草(cycloa peltata)是一种灌木,属于半边草科,俗称“足跖草”或“青环草”。自古以来,这种植物在传统医学中就被用作治疗各种疾病的草药,如皮肤感染、伤口、解热、利尿剂、糖尿病、哮喘、黄疸和蛇咬中毒。本研究的目的是表征水、甲醇和正己烷、二氯甲烷、丁醇、甲醇提取物的水馏分中存在的活性植物化学成分。为了分析有效的生物活性化合物,存在于提取物和馏分,傅里叶变换红外光谱被使用。定性植物化学筛选发现,水提物中存在甾体、生物碱、苷类、黄酮类、萜类、皂苷,甲醇提物中存在生物碱、酚类、单宁类、黄酮类、萜类、皂苷。该部位主要含有生物碱、酚类、单宁、黄酮类、萜类、皂苷等化学成分。红外光谱分析表明,化合物中存在醇类、酚类、胺类、羧酸类、醛类、酮类、烯烃、烷烃和芳香族化合物。研究结果表明,黄酮、萜类、生物碱、酚类是黄酮提取物和馏分中具有多种药理作用的活性成分。
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Phytopharmacological characterization of different extracts and fractions of Cyclea peltata
Cyclea peltata is a shrub belongs to Menispermiaceae family and is commonly known as “Pedal” or “Pada thalli”. The plant has been used since ancient times in traditional medicine as a healing herb for the treatment of various ailments such as skin infections, wounds, antipyretic, diuretic, diabetes, asthma, jaundice and snakebite poisoning. The objective of the present study was to characterize the active phytochemical constituents present in the aqueous, methanolic and n-hexane, dichloromethane, nbutanol, water fractions of methanolic extracts of C. peltata. To analyse the potent bioactive compounds, present in the extracts and fractions, Fourier Transform Infrared Spectroscopy was used. The qualitative phytochemical screening unveiled the presence of steroids, alkaloids, glycosides, flavonoids, terpenoids, saponins in aqueous extract and alkaloids, phenols, tannins, flavonoids, terpenoids, saponins in methanolic extract. The fractions of C. peltata showed the presence of alkaloids, phenols, tannins, flavonoids, terpenoids, saponins. The Infrared Spectroscopy profiling showed the presence of alcohols, phenols, amines, carboxylic acids, aldehydes, ketones, alkenes, alkanes and aromatic compounds. From the study, it is concluded that the bioactive compounds present in the extracts and fractions of C. peltata was alkaloids, phenols, flavonoids and terpenoids which is responsible for the diverse pharmacological properties.
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