恰蒂斯加尔邦报道的抗镰刀病草药与传统草药的比较筛选

D. Dash, A. Sahu, R. Panik, K. Mishra, P. Kashyap, Vaibhav Tripathi
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引用次数: 0

摘要

镰状细胞性贫血(SCA)是全世界公认的一种严重的遗传性疾病。这种基因异常出现在血红蛋白β链的第6个位置,在那里氨基酸缬氨酸被谷氨酸取代。SCA已被宣布为恰蒂斯加尔邦的一种地方病。恰蒂斯加尔邦以其丰富的草本植物资源而闻名。人们使用草药系统治疗镰状细胞性贫血。民间治疗师对草药和食物植物有良好的了解,他们多年来一直在镰状贫血患者身上实践这种营养保健品。目前的综述都是关于报道和传统草药。此外,我们还对一些传统草药进行了植物化学筛选,这些草药正在被治疗师使用。在筛选数据的基础上,我们比较了报道和传统草药的生物成分。因此,目前的工作包括审查和比较数据。本文的研究成果将有助于新出芽的研究人员进一步评价这类植物的抗镰刀病活性。关键词:镰状细胞性贫血,地方病,中医,营养药品,植物化学筛选
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Comparative screening of anti-sickling reported and traditional herbs found in Chhattisgarh
Sickle cell anaemia (SCA) has been recognized as a serious genetic disorder throughout the World. This genetic abnormality arises at the sixth position of β-chain of haemoglobin, where amino acid valine is replaced by glutamic acid. SCA has already been announced as an endemic in Chhattisgarh state. Chhattisgarh is well known for its enriched source of herbal plants. People use herbal system of medicine for the management of sickle cell anaemia. Folk healers have sound knowledge of herbal and food plants and they have been practicing such nutraceuticals on sickle anaemic patients for many years. Present review is all about reported and traditional herb. Moreover, we have performed phytochemical screening of some traditional herbs which are being used by the healer’s. on the basis of screening data we have compared the bio-constituents of both reported and traditional herbs. Thus, the present work has encompassed review as well as comparative data. This paper will be beneficial for the new budding researchers for the further assessment of such plants for their anti-sickling activity. Keywords: Sickle cell anaemia, Endemic, Traditional healers, Nutraceuticals, Phytochemical screening.
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