细胞外基质支架-干细胞再生治疗中的组织特异性生物活性生态位

Yehonatan Zur, Tzila Davidov, L. Baruch, M. Machluf
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引用次数: 0

摘要

为了恢复病变或损伤组织的正常功能,再生治疗方法通常基于复杂的仿组织移植物工程,包括生物材料支架、干细胞或它们的组合[1-4]。由于干细胞在生理再生机制中的主要作用,再生治疗通常依赖于干细胞移植或从邻近组织募集干细胞到植入支架
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Extracellular Matrix Scaffolds - A Tissue-Specific Bioactive Niche for Stem Cells in Regenerative Therapy
Aiming to restore the normal function of diseased or injured tissues, regenerative therapy approaches are generally based on the engineering of complex tissue-mimicking grafts, encompassing biomaterial scaffolds, stem cells, or their combinations [1-4]. Due to the major role of stem cells in physiological regenerative mechanisms, regenerative therapies normally rely on either stem cells transplantation or stem cell recruitment from the neighboring tissue into the implanted scaffold
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