Helmóz R. Appelt, J. S. Oliveira, R. Santos, O. Rodrigues, M. Z. Santos, E. Heck, L. C. Rosa
{"title":"碳水化合物基席夫碱的合成及其抗菌活性:糖段的重要性","authors":"Helmóz R. Appelt, J. S. Oliveira, R. Santos, O. Rodrigues, M. Z. Santos, E. Heck, L. C. Rosa","doi":"10.1155/2013/320892","DOIUrl":null,"url":null,"abstract":"A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.","PeriodicalId":13788,"journal":{"name":"International Journal of Carbohydrate Chemistry","volume":"2 1","pages":"1-5"},"PeriodicalIF":0.0000,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"17","resultStr":"{\"title\":\"Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety\",\"authors\":\"Helmóz R. Appelt, J. S. Oliveira, R. Santos, O. Rodrigues, M. Z. Santos, E. Heck, L. C. Rosa\",\"doi\":\"10.1155/2013/320892\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.\",\"PeriodicalId\":13788,\"journal\":{\"name\":\"International Journal of Carbohydrate Chemistry\",\"volume\":\"2 1\",\"pages\":\"1-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-12-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"17\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Carbohydrate Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2013/320892\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Carbohydrate Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2013/320892","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety
A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.
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