大疱性类天疱疮:诊断、治疗和管理

L. Hartman, Cynthia F. Griffith, Loderick A. Matthews
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引用次数: 0

摘要

大疱性类天疱疮是一种罕见的自身免疫性慢性皮肤病,以起泡、荨麻疹和瘙痒为特征,是所有类天疱疮疾病中最常见的。在过去的二十年中,BP的患病率一直在增长,主要是由于老年患者人数的增加和某些药物的暴露,如二肽基肽酶- iv (DDP-IV)抑制剂或“格列汀”,这些药物与大疱性类天疱疮的发病有关。这两个因素都导致潜在的BP病例增加,这强调了皮肤科卫生保健提供者熟悉这种疾病的临床表现、病因、诊断工具和治疗方法的必要性。这篇文章描述了BP的临床表现、病因、诊断检查和治疗,并包括一个病人的小特写来进一步说明疾病的表现和管理。
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Bullous Pemphigoid: Diagnosis, Treatment, and Management
Bullous pemphigoid, a rare autoimmune chronic skin disorder characterized by blistering, urticarial lesions (hives), and itching, is the most common among all pemphigoid diseases. BP has been growing in prevalence over the past two decades primarily due to an increasing elderly patient population and exposure to certain medication classes, such as dipeptidyl peptidase-IV (DDP-IV) inhibitors or “gliptins,” that are associated with bullous pemphigoid onset. Both of these factors contributing to a rise in potential BP cases underscores the need for health care providers in dermatology to be familiar with the clinical presentation, causes, diagnostic tools, and treatments for this condition. This article describes clinical manifestations, causes, diagnostic work-up, and treatment for BP, and includes a patient vignette to further illustrate disease presentation and management.
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