真光束STx直线加速器的Winston-Lutz-Gao试验

Jun-fang Gao, Xiaoqian Liu
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引用次数: 12

摘要

在基于直线加速器的立体定向放射外科(SRS)和立体定向体放射治疗(SBRT)方案中,单等中心多转移治疗因其治疗时间上的高效性而越来越受到人们的欢迎。然而,缺乏全面的质量保证计划仍然是医学物理学家面临的挑战。我们两年前开发的Winston-Lutz-Gao测试,在本研究中首次在True Beam STx (Varian Medical System)直线加速器上进行。横梁由Eclipse设计,带有龙门架、准直器和沙发旋转,沙发上放置了一个200磅的重物来模拟真实的治疗。来自Brainlab公司的“无框SRS QA目标指针”,在中心嵌入一个3.5毫米的金属球,被用作幻影。图像由内置直线加速器的门户成像仪获取,并由ARIA中的图像浏览器直接进行分析。我们发现,离直线中心越远的转移灶,光束力学与辐射中心的一致性越差。根据AAPM TG-142和美国放射肿瘤学会(ASTRO)白皮书标准,最远转移应在距直线等中心6cm以内。据我们所知,这是在True Beam STx直线加速器上进行的第一次离等中心温斯顿-卢茨测试。
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Winston-Lutz-Gao Test on the True Beam STx Linear Accelerator
In the linear accelerator-based stereotactic radio surgery (SRS) and stereotactic body radiotherapy (SBRT) programs, single isocenter-multiple metastases’ treatment has become more and more popular due to their high efficiency in treatment time. However, the absence of a comprehensive quality assurance program is still the challenge for medical physicists. The Winston-Lutz-Gao test, which we developed two years ago, was performed for the first time on a True Beam STx (Varian Medical System) linear accelerator in this study. Beams were designed by Eclipse with gantry, collimator, and couch full rotations, and a 200-pound weight was placed on the couch to mimic real treatment. The “frameless SRS QA target pointer” from the Brainlab company, with a 3.5-mm metallic ball embedded in the center, was used as a phantom. Images were acquired by the portal imager built-in linear accelerator and analyzed directly by the Image browser in ARIA. We found that the farther the metastases were from the linac isocenter, the worse the congruence was between the beam mechanical and the radiation center. The farthest metastases should be within 6 cm from the linac isocenter per the AAPM TG-142 and American Society for Radiation Oncology (ASTRO) white paper criteria. To the best of our knowledge, this is the first off-isocenter Winston-Lutz test performed on a True Beam STx linear accelerator.
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