球后脂质体两性霉素在COVID - 19阳性糖尿病患者眶尖综合征中的作用

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引用次数: 3

摘要

由严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)引起的2019冠状病毒病已被发现具有多种表现,影响多个器官系统。毛霉病是一种进展迅速的疾病,常见于免疫功能低下患者或糖尿病患者,预后不佳。本报告基于一个有趣的病例,该病例为37岁男性,患有毛霉病继发的眶尖综合征并合并感染COVID-19。我们讨论了在鼻-眶-毛霉菌病的情况下,除了全身抗真菌药物外,通过球后注射给药脂质体两性霉素的好处。
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The Role of Retrobulbar Liposomal Amphotericin in Orbital Apex Syndrome in a COVID – 19 Positive Diabetic
Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been seen to have varied presentation affecting multiple organ systems. Mucormycosis is a rapidly progressive disease often seen in immunocompromised patients or those with diabetes mellitus with guarded prognosis. This report is based on an interesting case of a 37-year-old man with orbital apex syndrome secondary to mucormycosis and co-infection with COVID-19. We discuss the benefit of administering liposomal amphotericin via retrobulbar injection in addition to systemic antifungals in the setting of rhino-orbital-mucormycosis.
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