[2型糖尿病的心血管死亡风险]。

N. V. Zeinalova, Yagub Ziyaddin Kurbanov, V. A. Mirzazade, R. A. Rzayeva, M. S. Novruzova
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引用次数: 2

摘要

目的基于Framingham风险评分评价代谢紊乱对2型糖尿病患者心血管死亡风险的影响。我们分析了1997-2014年在VM内分泌中心就诊的210名男性和210名女性2型糖尿病患者的检查结果。在人数、性别、年龄、身高等方面与真实患者相匹配,形成虚拟对照组,使患者的身体质量指数、总胆固醇、高密度脂蛋白胆固醇水平达到理想水平。2型糖尿病患者心血管死亡的平均风险为4,56±0,254%,而虚拟对照组为0,6±1,028%。差异有统计学意义(p < 0.001)。两组患者的最小风险分别估计为0.001%和0.01%。糖尿病患者心血管死亡的最大风险为34.17%,对照组为8.24%。由此可见,2型糖尿病及相关代谢紊乱显著增加心血管死亡风险。
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[The risk of cardiovascular death in type 2 diabetes].
Aim To evaluate effects of metabolic disorders on the risk of cardiovascular death in patients with type II diabetes based on Framingham risk score. We analyzed results of examination of 210 men and 210 women with type 2 diabetes who applied for medical care to the VM center of Endocrinology during 1997-2014. A virtual control group was formed matching real patients in terms of the number, sex, age, and height having ideal body mass index, total cholesterol and high-density lipoprotein cholesterol levels. The average risk of cardiovascular death in patients with type 2 diabetes was equal to 4,56±0,254% compared with 0,6±1,028% in the virtual control group. The differences was significant (p <0,001). The minimum risk for the patients of the two groups was estimated at 0,001% and 0,01% respectively. The maximum risk of cardiovascular death is 34,17% in patients with diabetes and 8,24% in controls. It is concluded that type 2 diabetes and related metabolic disorders significantly increase the risk of cardiovascular death.
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