对多囊卵巢综合征(PCOS)中子宫间隔的患病率进行分析,共49例

F. Al-Rshoud, Rami Kilani, Fida Al-Asali, Ibrahim Alsharaydeh
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摘要

目的了解在中东等高发地区,多囊卵巢综合征(PCOS)诱导排卵致孕失败后不孕的患者中子宫间隔的发生率。方法选取2017年9月至2018年7月在约旦安曼一家专门生育诊所就诊的172例确诊多囊卵巢综合征患者中的49例,通过子宫输卵管造影(HSG)筛查是否存在先天性子宫异常。这些异常是根据美国生育学会的分类进行分类的。如果怀疑有异常,则进行诊断性腹腔镜和宫腔镜检查以确认诊断。结果49例确诊为多囊卵巢综合征的患者中有15例(31%)确诊为子宫异常;11例为子宫隔,3例为弓形子宫,1例为双角形子宫。结论PCOS与子宫间隔有一定的相关性。本研究希望能让不孕不育的临床医生了解多囊卵巢综合征(PCOS)患者(31%)子宫因子的存在,以及在进行耗时且昂贵的促排卵过程之前,在第一次咨询时筛查这种先天性异常的必要性。
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The prevalence of uterine septum in polycystic ovarian syndrome (PCOS), a series of 49 cases
Objective To estimate the prevalence of uterine septum in patients with polycystic ovarian syndrome(PCOS) that were investigated for infertility after failure to achieve pregnancy with ovulation induction in a highincidence area, such as Middle East. Design A prospective observational study Methods A 49 patients from a total of 172 patients seeking fertility advice at a specialised fertility clinic in Amman, Jordan, during the period of September 2017 to July 2018 with confirmed polycystic ovarian syndrome were screened for the presence of congenital uterine anomalies by a hysterosalpingogram(HSG). The anomalies were classified according to the American Fertility Society classification. If an anomaly was suspected a diagnostic laparoscopy and hysteroscopy were performed to confirm the diagnosis. Results 15 patients (31%) of the 49 patients with confirmed diagnosis of polycystic ovarian syndrome were confirmed to have uterine anomalies; 11 patients had a uterine septum, three patients had an arcuate uterus and one patient had a bicornuate uterus. Conclusion There is association between PCOS and uterine septum. This study hopes to enlighten infertility clinicians about the presence of uterine factor in PCOS patients (31%) and the need to screen for this congenital anomaly at their first consultation before embarking on the time-consuming and costly process of ovulation induction.
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