简短的沟通

Peter Praamsma
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引用次数: 0

摘要

提出了一种简便的一锅法合成-溴丙烯酸酯,并与仲环胺经迈克尔加成转化为-溴取代β-氨基酸酯。在胺类中,morpholine是最合适的。
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Brief communications
A convenient one-pot synthesis of  -bromoacrylic acid esters followed by their conver-sion into  -bromo-substituted β-amino acid esters via Michael addition with secondary cyclic amines is proposed. Among the amines, morpholine turned most suitable.
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