动脉粥样硬化斑块的MRI和表征:新兴应用和分子成像

R. Choudhury, V. Fuster, J. Badimón, E. Fisher, Z. Fayad
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引用次数: 151

摘要

无创高分辨率磁共振具有成像动脉粥样硬化斑块和确定其组成和显微解剖的潜力。本文综述了斑块成像的基本原理,并通过使用现有的MRI技术描述了斑块的特征。介绍了核磁共振成像在人类疾病和动物模型中的应用,特别是在兔子和小鼠中。本文还讨论了MRI在实时血管介入、新型造影剂和分子成像等方面的应用。
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MRI and Characterization of Atherosclerotic Plaque: Emerging Applications and Molecular Imaging
Noninvasive high-resolution magnetic resonance has the potential to image atherosclerotic plaque and to determine its composition and microanatomy. This review summarizes the rationale for plaque imaging and describes the characteristics of plaque by use of existing MRI techniques. The use of MRI in human disease and in animal models, particularly in rabbits and mice, is presented. Present and future applications of MRI, including real-time vascular intervention, new contrast agents, and molecular imaging, are also discussed.
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