口腔给药系统的现有方法

Shrutika M. Gawas, A. Dev, G. Deshmukh, S. Rathod
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引用次数: 12

摘要

口腔给药是指通过口腔的口腔粘膜给药。本文的目的是通过讨论口腔黏膜的结构和环境,强调药物渗透的机制和口腔制剂的评估方法来回顾口腔给药。本文还简要介绍了口腔给药的优点、局限性、粘膜黏附的相关理论,以及黏附系统的制备方法、黏附聚合物和口腔系统的分类。
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CURRENT APPROACHES IN BUCCAL DRUG DELIVERY SYSTEM
Buccal delivery involves the administration of the desired drug through the buccal mucosal membrane lining of the oral cavity. The objective of this article is to review buccal drug delivery by discussing the structure and environment of the oral mucosa and highlighting the mechanisms of drug permeation and methodology in evaluating buccal formulations. This review also highlights a brief description of advantages, limitations of buccal drug delivery and theories involved in mucoadhesion along with method of preparation mucoadhesive system, mucoadhesive polymer, and classification of buccal system.
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