Merkel Cell Carcinoma of the Upper Eyelid: A Case Report and Review of the Literature

Introduction: Merkel cell carcinoma of the upper eyelid is a rare and aggressive tumor. It develops from Merkel cells present in areas with glabrous skin. It touches females more than males. Presentation of case: A 42 years old female patient presented with a nodular painless and purplish lesion of the left upper eyelid. The diagnosis of Merkel cell carcinoma was made on histopathological examination and immunohistochemical analysis. Discussion: Large resection in free margins associated with radiotherapy allow control of the tumor at 6 months after treatment. Propeller flap, free tarsal graft and tarsoconjonctival flap are used for full recovery of form and function of the left upper eyelid. Conclusion: Aggressive surgical approach is mandatory to control extension of localized MCC of the eyelid which is a lymphophilic and potentially metastatic lesion.