染色体15q23-q24上心脏富集转录物C15orf5的鉴定

DNA Sequence Pub Date : 2001-01-01 DOI:10.3109/10425170109042052

L. Carim-Todd, L. Sumoy, N. Andreu, Xavier Estivill And, M. Escarceller

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引用次数: 1

摘要

我们已经分离出C15orf5，这是一种新的人类基因，与任何已知的蛋白质都缺乏同源性。C15orf5基因编码一个1519 nt的转录本，ORF为94个氨基酸，预测蛋白大小为11.5 kDa。Northern blot分析显示C15orf5在心脏组织中的表达增强。使用Stanford TNG4辐射杂交面板将C15orf5定位到染色体15q23-q24上。

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Identification of C15orf5, a Heart-Enriched Transcript on Chromosome 15q23-q24

We have isolated C15orf5, a novel human gene lacking homology to any known protein. The C15orf5 gene encodes a transcript of 1, 519 nt with an ORF of 94 amino acids and a predicted protein size of 11.5 kDa. Northern blot analysis showed enhanced expression of C15orf5 in heart. C15orf5 was mapped to chromosome 15q23-q24 using the Stanford TNG4 Radiation Hybrid panel.

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DNA Sequence

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