卵黄囊的大小和形状作为妊娠结局的预测因子

Merehan Hewidy, Mohammed Mohesen, Hamada Ashry A Ali
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摘要

背景:据估计,大约30%至40%的植入妊娠在妊娠早期导致自然流产,其中大多数发生在妊娠早期。大量的丧失主要发生在妊娠早期,但一旦胚胎心脏活动出现,自然流产率逐渐下降到2-5%。方法:本研究于2020年2月至2020年8月在10月6日医院妇产科进行,对妊娠5周的46例患者行阴道超声检查,测定卵黄囊大小和形态。在怀孕6、9、12周时对孕妇进行记录。研究目的:评价卵黄囊对妊娠结局的预测价值。结果:11例患者出现卵黄囊形状异常,6周时流产组平均YSD为3.5±1.8,继续妊娠组平均YSD为2.2±0.4,差异有统计学意义,6周时截断点为2.8,而流产组与9、12周继续妊娠组的YSD差异无统计学意义。结论:妊娠6周卵黄囊大小较大,卵黄囊形态异常是妊娠结局不良的预测因素。
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Size and Shape of yolk sac as a predictor of pregnancy outcome
: Background: it is estimated that approximately 30% to 40% of implanted pregnancies resulted in spontaneous abortion during the first trimester, most of which occur in very early stage. Significant number of losses predominantly occurs very early in gestation, but once the embryonic heart activity appears the rate of spontaneous abortion gradually decreases to 2-5% . Methods: the present study was conducted at the Department of Obstetrics and Gynecology,6october Hospital during the period between February 2020 and august 2020 .46 cases at 5 weeks of pregnancy were subjected to transvaginal ultrasound and yolk sac size and shape were determined . Records of pregnant women were registered at 6, 9, 12 weeks of pregnancy. Aim Of The Work: to evaluate the value of yolk sac in prediction of pregnancy outcome . Results: Abnormal Shape of yolk sac was found in 11 cases, the mean YSD at 6 weeks in aborted cases was 3.5±1.8 and cases who continued pregnancy was 2.2 ±0.4 and this difference is statistically significant and cut off point at 6 weeks was 2.8 while there was no significant difference between YSD in aborted cases and in those who continued pregnancy at 9,12 weeks respectively. Conclusion: large size of yolk sac at 6 weeks of pregnancy and abnormal shape of yolk sac are predictor of poor pregnancy outcome.
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