{"title":"玻璃体内注射雷尼珠单抗辅助23号玻璃体切除联合ahmed青光眼瓣膜植入术治疗新生血管性青光眼","authors":"Jie Guo, Qiuming Li","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.06.018","DOIUrl":null,"url":null,"abstract":"Objective \nTo observe the effects of intravitreal Ranibizumab injection (IVR) as an Adjuvant combined 23-gauge vitrectomy (23G-TSV) and Ahmed glaucoma valve (AGV) implantation for Neovascular Glaucoma (NVG). \n \n \nMethods \nTwenty-five patients (25 eyes) of NVG with vitreous hemorrhage (VH) underwent IVR combined with 23G-TSV and AGV implantation. \n \n \nResults \nThe neovascularization of iris and anterior chamber angle in all patients completely or partly disappeared one week after IVR. At last visit, BCVA was improved compared with pre-operative BCVA; the IOP was significantly decreased after surgery; The surgical success rate was 88.0%. No serious complication occurred. \n \n \nConclusions \nFor stage Ⅲ NVG with VH, IVR as an adjuvant combined 23G-TSV and AGV implantation is safe and effective. \n \n \nKey words: \nGlaucoma; Neovascular; Implants; Ahmed; Vitrectomy; 23G; Ranibizumab","PeriodicalId":10236,"journal":{"name":"中国实用眼科杂志","volume":"36 1","pages":"617-621"},"PeriodicalIF":0.0000,"publicationDate":"2017-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Intravitreal ranibizumab injection as an adjuvant combined 23-gauge vitrectomy and ahmed glaucoma valve implantation in the treatment of neovascular glaucoma\",\"authors\":\"Jie Guo, Qiuming Li\",\"doi\":\"10.3760/CMA.J.ISSN.1006-4443.2017.06.018\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nTo observe the effects of intravitreal Ranibizumab injection (IVR) as an Adjuvant combined 23-gauge vitrectomy (23G-TSV) and Ahmed glaucoma valve (AGV) implantation for Neovascular Glaucoma (NVG). \\n \\n \\nMethods \\nTwenty-five patients (25 eyes) of NVG with vitreous hemorrhage (VH) underwent IVR combined with 23G-TSV and AGV implantation. \\n \\n \\nResults \\nThe neovascularization of iris and anterior chamber angle in all patients completely or partly disappeared one week after IVR. At last visit, BCVA was improved compared with pre-operative BCVA; the IOP was significantly decreased after surgery; The surgical success rate was 88.0%. No serious complication occurred. \\n \\n \\nConclusions \\nFor stage Ⅲ NVG with VH, IVR as an adjuvant combined 23G-TSV and AGV implantation is safe and effective. \\n \\n \\nKey words: \\nGlaucoma; Neovascular; Implants; Ahmed; Vitrectomy; 23G; Ranibizumab\",\"PeriodicalId\":10236,\"journal\":{\"name\":\"中国实用眼科杂志\",\"volume\":\"36 1\",\"pages\":\"617-621\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国实用眼科杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.06.018\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国实用眼科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.06.018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Intravitreal ranibizumab injection as an adjuvant combined 23-gauge vitrectomy and ahmed glaucoma valve implantation in the treatment of neovascular glaucoma
Objective
To observe the effects of intravitreal Ranibizumab injection (IVR) as an Adjuvant combined 23-gauge vitrectomy (23G-TSV) and Ahmed glaucoma valve (AGV) implantation for Neovascular Glaucoma (NVG).
Methods
Twenty-five patients (25 eyes) of NVG with vitreous hemorrhage (VH) underwent IVR combined with 23G-TSV and AGV implantation.
Results
The neovascularization of iris and anterior chamber angle in all patients completely or partly disappeared one week after IVR. At last visit, BCVA was improved compared with pre-operative BCVA; the IOP was significantly decreased after surgery; The surgical success rate was 88.0%. No serious complication occurred.
Conclusions
For stage Ⅲ NVG with VH, IVR as an adjuvant combined 23G-TSV and AGV implantation is safe and effective.
Key words:
Glaucoma; Neovascular; Implants; Ahmed; Vitrectomy; 23G; Ranibizumab