胚胎移植过程持续时间对着床成功的影响

I. Kasapoğlu, K. Aslan, A. Orhan, Ozge Albayrak, Seyma Haskoylu, G. Kuspinar, B. Avcı, G. Uncu
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摘要

目的:评价标准胚胎移植方法与简易胚胎移植方法对胚胎移植时间的影响。研究设计:本研究是一项回顾性队列研究,于2018年6月至2018年9月在一所高等艺术中心进行。第5天新鲜胚胎移植患者年龄在18 - 40岁之间,BMI <35 kg/m2,无子宫病理。患者分为两组。第一组为种植成功的患者,第二组为未种植的患者。各组按胚胎移植时间进行比较。92名患者参加了这项研究。还有as的子步骤;清除宫颈粘液,将外置导管置入宫颈,将胚胎装入导管,胚胎装入与胚胎移植之间的时间,以及之后收回外置导管所花费的时间。结果:组1与组2在宫颈清扫时间、外置导管置入宫颈时间(分别为;63 SEC vs. 76 SEC;p=0.18),胚胎加载期(分别为;69秒vs. 71秒;p=0.46),胚胎装载和胚胎移植之间的时间(分别为;10秒vs 10秒;p=0.74,外置导管回撤(分别;25.5秒vs. 24秒;P =0.42,胚胎移植总时间(182sec vs. 182.5 sec;p = 0.55)。结论:胚胎移植时间与着床率无关。如果进行了高质量的胚胎移植,胚胎移植过程步骤的持续时间并不是一个区分因素。
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The Effect of Embryo Transfer Process Duration on Implantation Success
OBJECTIVE: To evaluate the effect of the embryo transfer duration of standard and simple embryo transfer method. STUDY DESIGN: This study was a retrospective cohort study conducted at a tertiary ART Centre, between June 2018- September 2018. Day 5 fresh embryo transferred patients aged between 18 - 40, BMI <35 kg/m2 without uterine pathology were enrolled in the study. Patients were divided into two groups. Group-1 consisted of patients who had successful implantation and Group-2 consisted of patients who did not have implantation. Groups were compared according to their embryo transfer durations. Ninety-two patients were enrolled in the study. Also, sub-steps of as; cleaning of the cervical mucus and placing the outer catheter in the cervix, loading the embryo to the catheter, the period between embryo loading and embryo transfer, and following that, time spent for retracting the outer catheter evaluated. RESULTS: Between Group-1 and Group-2, there was no significant difference for the period of cervical cleaning and placing the outer catheter into the cervix (Respectively; 63 sec vs. 76 sec; p=0.18), the period of embryo loading (Respectively; 69sec vs. 71sec; p=0.46), the period between embryo loading and embryo transfer (Respectively; 10 sec vs. 10 sec; p=0.74, retracing the outer catheter (Respectively; 25.5sec vs. 24sec; p=0.42 and the total period of embryo transfer (182sec vs. 182.5 sec; p=0.55). CONCLUSION: The embryo transfer duration is not related to implantation rates. The duration of the embryo transfer process steps is not a distinguishing factor if a good-quality embryo transfer is done.
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