木棉叶提取物的生药评价及自由基清除活性

Radhika Chikatipalli
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引用次数: 1

摘要

目的:对木棉叶提取物进行生药学研究和抗氧化活性研究。材料和方法:标准化参数的材料和方法采用美国官方分析化学家协会(AOAC)的方法。以抗坏血酸为标准评价其抗氧化活性,用福林-乔卡勒特法测定其总酚含量和总黄酮含量。结果:木棉地上部分提取物的植物化学定性筛选结果显示,木棉地上部分提取物中含有黄酮类化合物、皂苷类化合物、单宁类化合物和酚类化合物。不同木棉叶提取物的总酚含量和总黄酮含量结果表明,pet的TPC和TFC最高。醚提取物和提取物的自由基清除活性呈浓度梯度。结论:木棉叶提取物具有丰富的植物化学成分,具有良好的抗氧化活性。研究结果表明,木棉叶提取物可作为探索其植物化学活性和抗氧化活性的重要途径,是开发新药的重要天然化合物来源。
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Pharmacognostic evaluation and free radical scavenging activity of Bombax ceiba leaf extracts
Objective: The present study aims pharmacognostic investigations and antioxidant activity of Bombax ceiba leaf extracts. Materials and Methods: The materials and methods for standardization parameters were performed by the Association of Official Analytical Chemist (AOAC) methods. The antioxidant activity was evaluated by taking ascorbic acid as standard, total phenolic content and total flavonoid content were determined by Folin–Ciocalteu method. Results: The results of qualitative phytochemical screening of Bombax ceiba aerial part extracts showed the presence of important phytochemical compounds, namely, flavonoids, saponins, tannins, and phenolic compounds. The results of total phenolic content and total flavonoid content of different Bombax ceiba leaf extracts showed the highest TPC and TFC for pet. ether extract and the free radical scavenging activity of extracts is in concentration gradient. Conclusion: It is concluded that Bombax ceiba leaf extracts have a rich profile of phytochemicals with significant proximate composition and good antioxidant activity. The findings indicate that Bombax ceiba leaf extract can be taken as an initiative step for finding out the promising agents responsible for its phytochemical and antioxidant activities and could be an important source of natural compounds for the development of new drug.
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