绝经后妇女卵巢上皮间质细胞瘤的研究

Debora Chantada de la Fuente, María Angeles Peteiro Cancelo, Laura Juaneda-Magdalena Benavides, Lara Alberta Lista
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引用次数: 1

摘要

卵巢上皮间质细胞瘤占所有卵巢肿瘤的不到0.5%。这是一种主要影响年轻女性的肿瘤,她们大多数时候都有男性化的迹象。最近发现它与DICER1基因突变有关。在这个报告中,我们描述了一例无症状的61岁妇女,她在左卵巢发现异质囊性病变,接受了腹腔镜双侧切除。病变的显微镜检查显示,在卵巢门区有一个实性囊性肿瘤增生,由两种不同的混合细胞群(间质细胞和支持细胞)形成。这种肿瘤的预后通常很好,除非它表现出分化差和/或异源因子或网状模式。所以,这些肿瘤的推荐治疗方法是保守疗法。在我们的病例中,手术是根据病人的意愿进行的。
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Sertoli-Leydig Cell Tumor of the Ovary in a Postmenopausal Woman
Sertoli-Leydig cell tumor of the ovary represents less than 0.5% of all ovary neoplasms. It is a tumor that affects predominantly young woman, who most of the times associate signs of virilization. It has recently been associated with mutations in DICER1. In this report, we describe a case of Sertoli-Leydig cell tumor in an asymptomatic 61- year-oldwoman who underwent a laparoscopic bilateral anexectomy for a heterogenous cystic lesion found in her left ovary. The microscopic examination of the lesion, showed a solid-cystic tumoral proliferation in the region identified as ovarian hilum, formed by two distinct and intermixed cell populations (Leydig cells and Sertoli cells). The prognosis of this kind of tumor is usually good, unless it shows poor differentiation and/or heterologous elements or retiforme pattern. So, the recommended treatment of these tumors, is a conservative approach. In our case, the anexectomy was performed by expressed desire of the patient.
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