{"title":"佛山白念珠球化学成分分析及抗氧化活性研究","authors":"吴 静姝","doi":"10.12677/JOCR.2016.43010","DOIUrl":null,"url":null,"abstract":"在综述秃马勃属真菌化学成分研究的基础上，通过多种指示剂和显色剂的显色反应或沉淀反应对佛山白秃马勃化学成分进行了预分析，并通过羟自由基(•OH)和1,1-二苯基-2-苦肼基(DPPH)清除试验评价了其甲醇提取物的体外抗氧化活性。结果表明，佛山白秃马勃含有生物碱、甾体和萜类化合物，具有有效的抗氧化活性，对•OH和DPPH自由基的半数清除浓度(IC50)分别为241.55和418.63 μg/mL。 Based on review of chemical composition of the genus of Calvatia sp., the chemical constituents of the puffball Calvatia candida from Foshan were analyzed by pre-test tube method, and its antioxi-dant activities were evaluated by the biochemical assay of hydroxyl and DPPH radicals scavenging activity in vitro. The results show that, the puffball Calvatia candida from Foshan contain alkaloids, steroids and terpenoids, and have potent antioxidant activities with IC50 values of 241.55 (for •OH) and 418.63 (for DPPH) μg/mL, respectively.","PeriodicalId":16596,"journal":{"name":"Journal of Organic Chemistry Research","volume":"22 1","pages":"69-76"},"PeriodicalIF":0.0000,"publicationDate":"2016-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Chemical Constituents Pre-Analysis and Antioxidant Activity of the Puffball Calvatia candida from Foshan\",\"authors\":\"吴 静姝\",\"doi\":\"10.12677/JOCR.2016.43010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"在综述秃马勃属真菌化学成分研究的基础上，通过多种指示剂和显色剂的显色反应或沉淀反应对佛山白秃马勃化学成分进行了预分析，并通过羟自由基(•OH)和1,1-二苯基-2-苦肼基(DPPH)清除试验评价了其甲醇提取物的体外抗氧化活性。结果表明，佛山白秃马勃含有生物碱、甾体和萜类化合物，具有有效的抗氧化活性，对•OH和DPPH自由基的半数清除浓度(IC50)分别为241.55和418.63 μg/mL。 Based on review of chemical composition of the genus of Calvatia sp., the chemical constituents of the puffball Calvatia candida from Foshan were analyzed by pre-test tube method, and its antioxi-dant activities were evaluated by the biochemical assay of hydroxyl and DPPH radicals scavenging activity in vitro. The results show that, the puffball Calvatia candida from Foshan contain alkaloids, steroids and terpenoids, and have potent antioxidant activities with IC50 values of 241.55 (for •OH) and 418.63 (for DPPH) μg/mL, respectively.\",\"PeriodicalId\":16596,\"journal\":{\"name\":\"Journal of Organic Chemistry Research\",\"volume\":\"22 1\",\"pages\":\"69-76\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-09-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Organic Chemistry Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12677/JOCR.2016.43010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Organic Chemistry Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12677/JOCR.2016.43010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
摘要
在综述秃马勃属真菌化学成分研究的基础上，通过多种指示剂和显色剂的显色反应或沉淀反应对佛山白秃马勃化学成分进行了预分析，并通过羟自由基(•OH)和1,1-二苯基-2-苦肼基(DPPH)清除试验评价了其甲醇提取物的体外抗氧化活性。结果表明，佛山白秃马勃含有生物碱、甾体和萜类化合物，具有有效的抗氧化活性，对•OH和DPPH自由基的半数清除浓度(IC50)分别为241.55和418.63 μg/mL。 Based on review of chemical composition of the genus of Calvatia sp., the chemical constituents of the puffball Calvatia candida from Foshan were analyzed by pre-test tube method, and its antioxi-dant activities were evaluated by the biochemical assay of hydroxyl and DPPH radicals scavenging activity in vitro. The results show that, the puffball Calvatia candida from Foshan contain alkaloids, steroids and terpenoids, and have potent antioxidant activities with IC50 values of 241.55 (for •OH) and 418.63 (for DPPH) μg/mL, respectively.
Chemical Constituents Pre-Analysis and Antioxidant Activity of the Puffball Calvatia candida from Foshan
在综述秃马勃属真菌化学成分研究的基础上，通过多种指示剂和显色剂的显色反应或沉淀反应对佛山白秃马勃化学成分进行了预分析，并通过羟自由基(•OH)和1,1-二苯基-2-苦肼基(DPPH)清除试验评价了其甲醇提取物的体外抗氧化活性。结果表明，佛山白秃马勃含有生物碱、甾体和萜类化合物，具有有效的抗氧化活性，对•OH和DPPH自由基的半数清除浓度(IC50)分别为241.55和418.63 μg/mL。 Based on review of chemical composition of the genus of Calvatia sp., the chemical constituents of the puffball Calvatia candida from Foshan were analyzed by pre-test tube method, and its antioxi-dant activities were evaluated by the biochemical assay of hydroxyl and DPPH radicals scavenging activity in vitro. The results show that, the puffball Calvatia candida from Foshan contain alkaloids, steroids and terpenoids, and have potent antioxidant activities with IC50 values of 241.55 (for •OH) and 418.63 (for DPPH) μg/mL, respectively.
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