埃博拉病毒研究进展

Pallavi B Sadgir, Pradnya R Pawar, Prachi S Jondhale, Manisha N Sharmale, Priya Ambre, P. Phalke
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摘要

丝状病毒科的埃博拉病毒是导致埃博拉病毒病(EVD)的原因,这是一种致命的病毒性出血性疾病。由于移民的流行,该疾病已成为全球公共卫生威胁。受害者最初表现出模糊的流感样症状,然后死于休克和多器官衰竭。没有治疗埃博拉病毒病的既定程序;相反,只使用支持性和对症治疗。本文综述了埃博拉病毒的临床和口腔症状、诊断工具、鉴别诊断、预防措施和管理方案。从那以后,埃博拉病毒偶尔开始感染人类,造成多次流行。由于城市化的发展、森林地区的入侵以及与野生动物的亲密接触,埃博拉病毒的蔓延已经导致动物和人类最致命的疾病。埃博拉病毒病(EVD)迄今已夺去无数人的生命,整个非洲大陆的病例数量不断增加。因此,进行了一项研究,以评估批准用于治疗埃博拉病毒病的药物的有效性和安全性、埃博拉病毒病暴发的趋势、埃博拉病毒病患者的发病率和死亡率以及其他因素。
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A review on ebola virus
The Ebola virus of the Filoviridae family is the cause of Ebola virus disease (EVD), a deadly viral hemorrhagic sickness. Due to the prevalence of immigrants, the disease has become a global public health threat. The victims initially exhibit vague influenza-like symptoms before succumbing to shock and multiorgan failure. There is no established procedure for treating EVD; instead, only supportive and symptomatic therapy is used. The Ebola virus, including its clinical and oral symptoms, diagnostic tools, differential diagnoses, preventive measures, and management protocol, are thoroughly discussed in this review paper. Since then, the Ebola virus has occasionally started to infect humans, causing multiple epidemics. The expansion of the Ebola virus has resulted in the deadliest diseases for both animals and humans because of the growth of urbanization, invasion of forested areas, and intimate contact with wildlife creatures. The Ebola virus disease (EVD) has so far claimed the lives of numerous people, with an increased number of cases being seen throughout the African continent. Thus, a study was conducted to evaluate the efficacy and safety of medications approved for the treatment of EVD, trends in EVD outbreaks, morbidity and mortality among EVD patients, and other factors.
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